Results 51 to 60 of about 195,293 (269)

In vivo metabolism of LDL subfractions in patients with heterozygous FH on statin therapy

Journal of Lipid Research, 2004
LDL can be subfractionated into buoyant (1.020–1.029 g/ml−1), intermediate (1.030–1.040 g/ml−1), and dense (1.041–1.066 g/ml−1) LDLs. We studied the rebound of these LDL-subfractions after LDL apheresis in seven patients with heterozygous familial ...
H.C. Geiss, S. Bremer, P.H.R. Barrett, C. Otto, K.G. Parhofer   +4 more
doaj   +1 more source

Lipoprotein apheresis efficacy and challenges: single center experience

Hematology, Transfusion and Cell Therapy, 2022
Introduction: Lipoprotein apheresis (LA) is an extracorporeal therapy which removes apolipoprotein B-containing particles from the circulation. We evaluated techniques and efficiency of lipoprotein apheresis procedures applied to patients with familial ...
Zehra Narlı Özdemir, Uğur Şahin, Yasin Yıldırım, Cansın Tulunay Kaya, Osman İlhan   +4 more
doaj   +1 more source

Study of biochemical changes after plateletpheresis in healthy male donors [PDF]

, 2018
BACKGROUND: There is relatively little information about endogenous biochemical changes in a response to plateletpheresis in healthy donors. We aimed to investigate the changes in different biochemical parameters including glycemic status, insulin ...
Al Sofyani, A, Alrowali, D, Bahijri, S, Balloon, D, Borai, A, Farzal, A, Ferns, G, Saleh, A   +7 more
core   +1 more source

Single Low-Density Lipoprotein Apheresis Does Not Improve Vascular Endothelial Function in Chronically Treated Hypercholesterolemic Patients

International Journal of Vascular Medicine, 2016
Objective. To investigate vascular endothelial function (VEF) responses to a single low-density lipoprotein (LDL) apheresis session in hypercholesterolemic patients undergoing chronic treatment. Methods. We measured brachial artery flow-mediated dilation
Kevin D. Ballard, Eunice Mah, Yi Guo, Richard S. Bruno, Beth A. Taylor, Jo Ellen Beam, Donna M. Polk, Paul D. Thompson   +7 more
doaj   +1 more source

Long‐term prognosis of focal segmental glomerulosclerosis treated with therapeutic low‐density lipoprotein‐apheresis in patients with severe kidney dysfunction and proteinuria

Rheumatology & Autoimmunity, 2023
Background The prognosis of focal segmental glomerulosclerosis patients with nephrotic syndrome is estimated to be 10%–20% in 5 years and 30%–50% in 10 years, leading to end‐stage kidney disease.
Shinji Kitajima, Megumi Osima, Hisayuki Ogura, Shiori Nakagawa, Yuta Yamamura, Taito Miyake, Taro Miyagawa, Tadashi Toyama, Akinori Hara, Norihiko Sakai, Miho Shimizu, Takashi Wada, Yasunori Iwata   +12 more
doaj   +1 more source

Recent Progress in Double Filtration Plasmapheresis

Hemodialysis International, Volume 30, Issue 1, Page 18-25, January 2026.
ABSTRACT Double‐filtration plasmapheresis is an advanced extracorporeal blood purification technique that selectively removes pathogenic macromolecules based on molecular weight. Unlike conventional plasma exchange, double‐filtration plasmapheresis uses a two‐step filtration process to retain beneficial plasma components such as albumin, while ...
Dan Li, Xiaoqiang Liu, Yuhan Wang, Wenxuan Ji   +3 more
wiley   +1 more source

Lipoprotein turnover and possible remnant accumulation in preeclampsia: insights from the Freiburg Preeclampsia H.E.L.P.-apheresis study

Lipids in Health and Disease, 2018
Background Preeclampsia is a life-threatening disease in pregnancy, and its complex pathomechanisms are poorly understood. In preeclampsia, lipid metabolism is substantially altered.
Christine Contini, Martin Jansen, Brigitte König, Filiz Markfeld-Erol, Mirjam Kunze, Stefan Zschiedrich, Ulrich Massing, Irmgard Merfort, Heinrich Prömpeler, Ulrich Pecks, Karl Winkler, Gerhard Pütz   +11 more
doaj   +1 more source

Pregnancy in a Woman with Homozygous Familial Hypercholesterolemia Not on Low-Density Lipoprotein Apheresis

American Journal of Perinatology Reports, 2012
Pregnancy in women with homozygous familial hypercholesterolemia (FH) has been rarely reported and might pose risks on the mother and her fetus. Although most reported cases remained on low-density lipoprotein (LDL) apheresis, there are no clear ...
Akl C. Fahed, Anwar H. Nassar
doaj   +1 more source

Efficient Scaling up EV‐AAVs Production via Cellular Nanoporation for Familial Hypercholesterolaemia Therapy

Journal of Extracellular Vesicles, Volume 14, Issue 11, November 2025.
ABSTRACT Adeno‐associated virus (AAV)–mediated gene therapies face critical clinical limitations, including immune‐mediated neutralization by pre‐existing antibodies and dose‐dependent hepatotoxicity. Extracellular vesicle‐encapsulated AAVs (EV‐AAVs) offer a promising solution by shielding AAVs from antibody recognition, yet existing production methods
Yuting Yan, Yi You, Shuhong Ma, Hui Yi, Guangduo Chen, Jie Ni, Changyan Chen, Wenyu Ke, Lingying Li, Rui Bai, Yuqing Ran, Wenjing Lu, Min Zhu, Yongshuai Zhang, Jing Dai, Man Qi, Feng Lan, Andrew S. Lee, Ran Zhang, Xujie Liu, Zhaoyang Chen   +20 more
wiley   +1 more source

Lipoprotein apheresis to treat elevated lipoprotein (a)1

Journal of Lipid Research, 2016
An elevated plasma concentration of lipoprotein (a) [Lp(a)] is an independent risk factor for cardiovascular disease. Life style modification and currently available drugs either fail to effectively lower plasma Lp(a) levels or do not result in clinical ...
Elisa Waldmann, Klaus G. Parhofer
doaj   +1 more source