Results 61 to 70 of about 3,049 (238)

Extracorporeal LDL-Cholesterol Elimination in the Treatment of Severe Familial Hypercholesterolemia

Acta Medica, 2003
The extracorporeal elimination of LDL-cholesterol could be performed using the classic non-selective centrifuge or membrane plasmapheresis. The modern methods are more selective and effective.
Milan Bláha
doaj   +1 more source

TabMixer: Excavating Label Distribution Learning with Small-scale Features [PDF]

arXiv, 2022
Label distribution learning (LDL) differs from multi-label learning which aims at representing the polysemy of instances by transforming single-label values into descriptive degrees. Unfortunately, the feature space of the label distribution dataset is affected by human factors and the inductive bias of the feature extractor causing uncertainty in the ...
arxiv  

Impacts of CD36 Variants on Plasma Lipid Levels and the Risk of Early‐Onset Coronary Artery Disease: A Systematic Review and Meta‐Analysis

Cardiovascular Therapeutics, Volume 2025, Issue 1, 2025.
Background: Recent studies have indicated that cluster of differentiation 36 (CD36) is closely linked to dyslipidemia and early‐onset coronary artery disease (EOCAD). This study is aimed at investigating the impacts of CD36 gene variants on lipid profiles and EOCAD risk.
Zhi Luo, Lingwei Lv, Victor Garcia
wiley   +1 more source

LDL-apheresis depletes apoE-HDL and pre-β1-HDL in familial hypercholesterolemia: relevance to atheroprotection

Journal of Lipid Research, 2011
Subnormal HDL-cholesterol (HDL-C) and apolipoprotein (apo)AI levels are characteristic of familial hypercholesterolemia (FH), reflecting perturbed intravascular metabolism with compositional anomalies in HDL particles, including apoE enrichment. Does LDL-
Alexina Orsoni, Samir Saheb, Johannes H.M. Levels, Geesje Dallinga-Thie, Marielle Atassi, Randa Bittar, Paul Robillard, Eric Bruckert, Anatol Kontush, Alain Carrié, M. John Chapman   +10 more
doaj  

Acute effects of low density lipoprotein apheresis on metabolic parameters of apolipoprotein B

Journal of Lipid Research, 2000
Apheresis is a treatment option for patients with severe hypercholesterolemia and coronary artery disease. It is unknown whether such therapy changes kinetic parameters of lipoprotein metabolism, such as apolipoprotein B (apoB) secretion rates ...
Klaus G. Parhofer, P. Hugh R. Barrett, Thomas Demant, Peter Schwandt   +3 more
doaj  

LDL: Line Distance Functions for Panoramic Localization [PDF]

arXiv, 2023
We introduce LDL, a fast and robust algorithm that localizes a panorama to a 3D map using line segments. LDL focuses on the sparse structural information of lines in the scene, which is robust to illumination changes and can potentially enable efficient computation.
arxiv  

Therapeutic and pharmacological applications of extracellular vesicles and lipoproteins

British Journal of Pharmacology, Volume 181, Issue 23, Page 4733-4749, December 2024.
Abstract In recent years, various approaches have been undertaken to eliminate lipoproteins co‐isolated with extracellular vesicles, as they were initially regarded as contaminating entities. However, novel discoveries are reshaping our perspective.
Krisztina Németh, Brachyahu M. Kestecher, Sayam Ghosal, Bernadett R. Bodnár, Ágnes Kittel, Szabolcs Hambalkó, Csenger Kovácsházi, Zoltán Giricz, Péter Ferdinandy, Xabier Osteikoetxea, Ralph Burkhardt, Edit I. Buzas, Evelyn Orsó   +12 more
wiley   +1 more source

Platelet aggregation and lipoprotein levels in a patient with familial hypercholescholesterolemia after selective LDL-apheresis

São Paulo Medical Journal
Platelet aggregation was studied in a patient with familial hypercholesterolemia immediately after aphereis selective for low-density lipoprotein (LDL), a lipid-lowering procedure.This treatment reduced plasmatic levels of total and LDL-cholesterol, apo ...
Madalena Nunes da Silva Pares, Elbio Antonio D'Amico, José Mauro Kutner, Dalton de Alencar Fischer Chamone, Sergio Paulo Bydlowski   +4 more
doaj   +1 more source

A novel small molecule phagocytosis inhibitor, KB‐208, ameliorates ITP in mouse models with similar efficacy as IVIG

Transfusion, Volume 64, Issue 12, Page 2233-2240, December 2024.
Abstract Background The characteristic feature of immune cytopenias involves the process of extravascular phagocytosis, wherein macrophages in the spleen and/or liver engage in the destruction of blood cells that have been opsonized by auto‐ or alloantibodies.
Melika Loriamini, Melissa M. Lewis‐Bakker, Beth Binnington, Lakshmi P. Kotra, Donald R. Branch   +4 more
wiley   +1 more source

Acute and chronic effects on cholesterol biosynthesis of LDL-apheresis with or without concomitant HMG-CoA reductase inhibitor therapy.

Journal of Lipid Research, 1994
To determine the acute and long-term effects of low density lipoprotein (LDL) reduction on cholesterol biosynthesis, we studied changes in the cholesterol precursors mevalonic acid (MVA) and lathosterol in patients with heterozygous familial ...
M Pfohl, R P Naoumova, C Klass, W Knisel, B Jakober, T Risler, G R Thompson   +6 more
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