Results 91 to 100 of about 2,625,160 (406)

Post-transcriptional regulation of retroviral vector-transduced low density lipoprotein receptor activity.

open access: yesJournal of Lipid Research, 1990
We have reported the use of a retroviral vector to introduce the low density lipoprotein (LDL) receptor gene into receptor-deficient Watanabe heritable hyperlipidemic (WHHL) rabbit fibroblasts (Miyanohara, A., M. F. Sharkey, D. Steinberg, J. L.
MF Sharkey   +4 more
doaj  

Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice

open access: yesJournal of Lipid Research, 2011
Non-alcoholic fatty liver disease (NAFLD), the hepatic manifestation of the metabolic syndrome, can progress to steatohepatitis (NASH) and advanced liver disease.
S. Subramanian   +11 more
semanticscholar   +1 more source

EFEKTIVITAS KOMBINASI DL-αTOKOFEROL DAN ASAM ASKORBAT TERHADAP KADAR LDL-OX, sCD36, sVCAM-1 DAN NO PADA ANAK SINDROM NEFROTIK [PDF]

open access: yes, 2015
Latar Belakang: Stres oksidatif, disfungsi endotel dan inflamasi mendasari proses aterosklerosis pada anak sindrom nefrotik (SN). Kombinasi dl-α-tokoferol dan asam askorbat berpotensi menurunkan proses stress oksidatif dan disfungsi endotel banyak ...
MELLYANA, Omega
core  

Apolipoprotein E: from cardiovascular disease to neurodegenerative disorders. [PDF]

open access: yes, 2016
Apolipoprotein (apo) E was initially described as a lipid transport protein and major ligand for low density lipoprotein (LDL) receptors with a role in cholesterol metabolism and cardiovascular disease.
Mahley, Robert W
core   +1 more source

Adropin: An endocrine link between the biological clock and cholesterol homeostasis [PDF]

open access: yes, 2018
This article explores two translation models circling around the key issue “equivalence” in translation studies. They are the Jerome Model and the Horace Model. They differentiate from each other in the aspects of the translating priorities and purposes,
et al,, Rao, D. C
core   +4 more sources

Lactate‐Activated GPR132‐Src Signal Induces Macrophage Senescence and Aggravates Atherosclerosis Under Diabetes

open access: yesAdvanced Science, EarlyView.
Elevated lactate in diabetes activates the GPR132‐Src pathway in macrophages, inducing macrophage senescence and further enhancing foam cell formation. This mechanism exacerbates atherosclerotic progression. Abstract Diabetes is widely acknowledged as a significant risk factor for atherosclerosis, facilitating plaque formation through various ...
Xiaofeng Ge   +10 more
wiley   +1 more source

Rapid fluorometric assay of LDL receptor activity by DiI-labeled LDL.

open access: yesJournal of Lipid Research, 1993
DiI-LDL (3,3'-dioctadecylindocarbocyanine-low density lipoprotein) has been extensively used in morphological and microscopic studies of receptor-mediated metabolism of LDL in many cell lines.
ZF Stephan, EC Yurachek
doaj  

Ezetimibe therapy: mechanism of action and clinical update. [PDF]

open access: yes, 2012
The lowering of low-density lipoprotein cholesterol (LDL-C) is the primary target of therapy in the primary and secondary prevention of cardiovascular events.
Dayspring, Thomas D   +2 more
core   +1 more source

Emerging Nanotechnology Strategies for Obesity Therapy

open access: yesAdvanced Science, EarlyView.
Three types of nanomaterials used for obesity treatment are highlighted, including inorganic nanomaterials, organic nanomaterials and biomimetic nanomaterials. A detailed and comprehensive introduction to the recent nanotechnology strategies for obesity management is also provided, including drug delivery, photodynamic therapy, hyperthermia, gas ...
Weili Chang   +5 more
wiley   +1 more source

Regulation of macrophage apoE secretion and sterol efflux by the LDL receptor

open access: yesJournal of Lipid Research, 2007
Factors that regulate apolipoprotein E (apoE) secretion by macrophages will have important effects on vessel wall lipid flux and atherosclerosis. Macrophages express the LDL receptor, which binds apoE with high affinity and could thereby affect the net ...
Danijela Lucic   +5 more
doaj  

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