Results 301 to 310 of about 2,612,734 (405)

Lipid and lipoprotein particle profiles in patients with type 2 diabetes mellitus: A comparative study between highlanders and lowlanders

open access: yesLipids, EarlyView.
Abstract The lipid profiles of highlanders and lowlanders differ. However, studies of the lipid profiles of patients with type 2 diabetes mellitus (T2DM) living at high altitudes are limited. This study aimed to compare lipid profiles and lipoprotein particles in individuals with T2DM permanently residing in the Tibetan Plateau and those residing in ...
Chenghui Zhang   +6 more
wiley   +1 more source

Efficacy and safety of low‐dose atorvastatin plus ezetimibe for primary hypercholesterolemia: A randomized, double‐blind, multicenter phase 3 trial

open access: yesLipids, EarlyView.
Low‐dose atorvastatin combined with ezetimibe achieves superior LDL‐C reduction (44.8%) compared with equivalent or higher‐dose statin monotherapy in Korean patients, presenting a more effective and safer therapeutic strategy potentially applicable to broader Asian populations.
Tae Oh Kim   +19 more
wiley   +1 more source

A novel oxidized LDL receptor

open access: yesJapanese Journal of Pharmacology, 1998
Tomoh Masaki, Tatsuya Sawamura
openaire   +2 more sources

Exogenous oxidized phytosterol may modulate linoleic acid metabolism through upregulation of fatty acid desaturase in rats

open access: yesLipids, EarlyView.
Abstract Previous in vitro studies have indicated that oxidized phytosterol (OPS) exhibits some toxicity; however, the harmful effects of OPS on fatty acid metabolism are not completely understood yet. Therefore, this study examined the effects of exogenous phytosterol (PS) and OPS on growth parameters and lipid metabolism in rats.
Tomonari Koyama, Kyoichi Osada
wiley   +1 more source

Breaking Boundaries: Chronic Diseases and the Frontiers of Immune Microenvironments

open access: yesMed Research, EarlyView.
ABSTRACT The immune microenvironment includes immune cells, cytokines, extracellular matrix, vesicles, etc. The interactions between these components form a unique local immune microecology. Although immunity serves as the defense against external pathogens, aberrant immune activation often contributes to disease development.
Guoqing Li   +13 more
wiley   +1 more source

DrugtargetMR, an Integrated Software for Identifying Genetic Determinants Underlying Human Complex Traits

open access: yesMed Research, EarlyView.
The DrugtargetMR integrates multiple models and methods through a comprehensive workflow that includes data preparation, core analysis, and visualization to identify disease‐associated susceptibility loci and genes, corresponding to the inner, middle, and outer circles, respectively.
Qiong Lyu   +3 more
wiley   +1 more source

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