Results 311 to 320 of about 2,621,020 (406)

Lipid and lipoprotein particle profiles in patients with type 2 diabetes mellitus: A comparative study between highlanders and lowlanders

open access: yesLipids, EarlyView.
Abstract The lipid profiles of highlanders and lowlanders differ. However, studies of the lipid profiles of patients with type 2 diabetes mellitus (T2DM) living at high altitudes are limited. This study aimed to compare lipid profiles and lipoprotein particles in individuals with T2DM permanently residing in the Tibetan Plateau and those residing in ...
Chenghui Zhang   +6 more
wiley   +1 more source

Efficacy and safety of low‐dose atorvastatin plus ezetimibe for primary hypercholesterolemia: A randomized, double‐blind, multicenter phase 3 trial

open access: yesLipids, EarlyView.
Low‐dose atorvastatin combined with ezetimibe achieves superior LDL‐C reduction (44.8%) compared with equivalent or higher‐dose statin monotherapy in Korean patients, presenting a more effective and safer therapeutic strategy potentially applicable to broader Asian populations.
Tae Oh Kim   +19 more
wiley   +1 more source

Exogenous oxidized phytosterol may modulate linoleic acid metabolism through upregulation of fatty acid desaturase in rats

open access: yesLipids, EarlyView.
Abstract Previous in vitro studies have indicated that oxidized phytosterol (OPS) exhibits some toxicity; however, the harmful effects of OPS on fatty acid metabolism are not completely understood yet. Therefore, this study examined the effects of exogenous phytosterol (PS) and OPS on growth parameters and lipid metabolism in rats.
Tomonari Koyama, Kyoichi Osada
wiley   +1 more source

Nutraceutical Blends Promote Weight Loss, Inflammation Reduction, and Better Sleep: The Role of Faecalibacterium prausnitzii in Overweight Adults–A Double‐Blind Trial

open access: yesMolecular Nutrition &Food Research, EarlyView.
This study explored how a 90‐day nutraceutical blend with prebiotics, minerals, and silymarin affects the gut‐brain axis in overweight adults. Results showed improved gut microbiota, reduced inflammation, and better sleep, mood, and quality of life, suggesting a strong link between gut health and mental well‐being.
Aline Boveto Santamarina   +15 more
wiley   +1 more source

LDL receptor-related protein, a multifunctional ApoE receptor, binds secreted β-amyloid precursor protein and mediates its degradation

open access: bronze, 1995
Maria Z. Kounnas   +7 more
openalex   +1 more source

Molecular basis for LDL receptor recognition by PCSK9

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2008
H. Kwon   +4 more
semanticscholar   +1 more source

Receptor-mediated cellular uptake of cyclosporine [PDF]

open access: yes, 1989
Diven, WF   +3 more
core  

Mediterranean Diet Modulates Gene Expression of Cholesterol Efflux Receptors in High‐Risk Cardiovascular Patients

open access: yesMolecular Nutrition &Food Research, EarlyView.
The graphical abstract (GA) displays the study of two randomized trials studying the molecular mechanisms of cholesterol efflux‐related genes analyzed via transcriptomics after two Mediterranean diet interventions. Cholesterol efflux molecules include ATP‐binding cassette transporters ABCA1 and ABCG1 in cholesterol transport to HDL. It also depicts the
Javier Hernando‐Redondo   +20 more
wiley   +1 more source

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