Results 141 to 150 of about 27,896 (277)
We report a proof‐of‐concept combination of topoisomerase inhibition and FLASH radiotherapy showing enhanced antitumor activity in head and neck carcinoma biomodels, supporting further investigation of this strategy in more clinically representative models and treatment settings. ABSTRACT Locally advanced head and neck carcinoma remains associated with
Patrizia Sarogni +17 more
wiley +1 more source
Prostate Cancer Development, Progression, and Therapy
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin +9 more
wiley +1 more source
Abstract Background While pencil beam scanning (PBS) with motion mitigation such as re‐scanning, breath hold, or gating is well established for treating moving targets in clinical practice, the precision for Spatially Fractionated Radiation Therapy (SFRT) using proton minibeams introduces presents a unique challenge.
Oxana Actis +7 more
wiley +1 more source
Therapeutic Efficacy of Metronomic Doxorubicin and Low Dose of Gamma Radiation on Breast Cancer Model. [PDF]
Abdelrahman IY +5 more
europepmc +1 more source
Robust optimization of catheter positions and dwell times for HDR prostate brachytherapy
Abstract Background HDR prostate brachytherapy plans are sensitive to catheter placement uncertainty, as discrepancies between planned and delivered catheter positions can degrade target coverage and increase organ at risk dose. Current inverse planning methods optimize dwell times for a fixed implant geometry and do not account for geometric ...
Joseph B. Schulz +3 more
wiley +1 more source
Defying the Unfavorable Risk: The Efficacy of LDR Brachytherapy Monotherapy in Gleason 7 Prostate Cancer: A 16-Year Single-Center Retrospective Study. [PDF]
Rabaça C +11 more
europepmc +1 more source
Dose modeling of superficial brachytherapy applicator geometries using multiple radioisotopes
Abstract Background Superficial brachytherapy enables localized dose delivery for superficial cutaneous lesions, but conventional applicators may be limited in treating extended, irregular, or curved surfaces. Geometric constraints, gaps or overlaps between adjacent applicators, and placement‐related uncertainties can reduce dose uniformity ...
Jin Jegal +5 more
wiley +1 more source
Survival outcomes of dogs with multicentric lymphoma treated with sequential half-body radiotherapy and L-CHOP without maintenance chemotherapy. [PDF]
Colosi J +8 more
europepmc +1 more source
Automatic Street Light Control System is a simple yet powerful concept, which uses transistor as a switch. By using this system manual works are 100% removed. It automatically switches ON lights when the sunlight goes below the visible region of our eyes. This is done by a sensor called Light Dependant Resistor (LDR).
openaire +1 more source

