Results 21 to 30 of about 152,512 (204)

La actividad alfarera en la ciudad de León durante los siglos medievales

open access: yesAnuario de Estudios Medievales, 2011
Este trabajo trata de ofrecer una visión multifocal y evolutiva sobre el desarrollo de la actividad alfarera en la ciudad de León y su alfoz durante los siglos medievales.
Raquel Martínez Peñín
doaj   +1 more source

La Hermandad General en León (1477-1504)

open access: yesCuadernos Medievales, 2023
El presente estudio versa sobre la Hermandad General de los Reyes Católicos y su consolidación, fundamento e impacto en la provincia de León, desde el año 1477 hasta 1504, coincidiendo con el reinado de Isabel I de Castilla.
Laura Díez Gutiérrez
doaj  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Arturo Alvarado y Jesica Vega (coords.), León, de la Ciudad a la Metrópoli

open access: yesOficio, Revista de Historia e Interdisciplina, 2022
Reseña a: Arturo Alvarado y Jesica Vega (coords.). León, de la Ciudad a la Metrópoli, México: Universidad de Guanajuato / Editorial Ítaca, 2021, 294 pp.
Carlos Cordourier Real
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Renacer entre leones: una nueva perspectiva de los leones de Pozo Moro (Chinchilla, Albacete)

open access: yesLucentum, 2009
En el presente trabajo se reflexiona sobre los sillares de esquina con forma de león que en su día formaron parte del conjunto monumental de Pozo Moro (Chinchilla, Albacete).
Jorge García Cardiel
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Apuntes para una reseña biográfica de Narcisa González Guzmán, una de las primeras mujeres del Opus Dei / Notes for a biographical analysis of Narcisa González Guzmán, one of the first women in Opus Dei [PDF]

open access: yesStudia et Documenta, 2010
Narcisa (Nisa) González Guzmán (1907-1998), was one of the first women in Opus Dei. The article focuses on the 1907-1942 period of her life and provides information on her family, the education she received and her activities as well as her meeting with ...
Francisca R. Quiroga
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Primera cita de la especie amenazada Cucujus cinnaberinus (Scopoli, 1763) en la provincia de León y tercera para España (Coleoptera, Cucujidae)

open access: yesBoletín de la Asociación Española de Entomología
Se registra Cucujus cinnaberinus (Scopoli, 1763) en la provincia de León (España) lo que constituye la tercera cita ibérica de esta amenazada y emblemática especie, que se describe aquí, aportando detalles sobre su bionomía, hábitat y desarrollo.
Jorge Ángel Ramos-Abuin
doaj   +1 more source

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