Results 151 to 160 of about 15,025,179 (334)

Effect of Lead Poisoning on the Thiamine Status and Function in Liver and Blood of Rats. [PDF]

, 1978
Elisabeth Tokarski, L. Reio, Nils Ellfolk, Vernon D. Parker, André Babadjamian, Jacques Metzger   +5 more
openalex   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Barun Mitra, Kendra Okonski and Mohit Satyanand eds, Keeping the Water Flowing: Understanding the role of Institutions, Incentives, Economics and Entrepreneurship in Ensuring Access and Optimising Utilisation of Water (New Delhi: Academic Foundation, 2007) - Book Review [PDF]

Law, Environment and Development Journal, 2007
Reviewed by Usha Ramanathan, LEAD Journal
doaj  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

TYPOS CORRECTED SC5: 'Erroneous assumptions lead to fundamentally flawed hydrogeological conclusions'

, 2016
David Smythe, Paul L. Younger, C Bilcalho, A Clarke, J Ellis, I Mannino, J Johnston, M Felix, P Younger, A Vaughan, R Mair, M Bickle, D Goodman, B Koppelman, J Roberts, R Selley, Z Shipton, H Thomas, A Walker, E Woods, P Younger, A Spencer, V Larsen, Y Yang, A Aplin, P Younger, P Younger   +26 more
openalex   +1 more source

Lead induced modulation of splenic macrophage responses on humoral and cell mediated immunity [PDF]

, 2004
Biswadev Bishayi, Mahuya Sengupta, Soumya Ghosh   +2 more
openalex   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

How to Report Methods to an Interdisciplinary Audience: Machine Learning

iScience, 2020
Simona Fiorani, Stefano Tonzani
doaj   +1 more source