Results 161 to 170 of about 15,025,179 (334)

P188 OUTCOMES OF TRANSVENOUS LEAD EXTRACTION IN OCTOGENARIANS USING BIDIRECTIONAL ROTATIONAL MECHANICAL SHEATHS [PDF]

, 2023
Federico Migliore, R Pittorru, P Dell‘Aglio, Manuel De Lazzari, Sabino Iliceto, Emanuele Bertaglia, Gino Gerosa, Vincenzo Tarzia, D Carretta   +8 more
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Ameliorative Effect of Methanol Extract of Tiger Nut (Cyperus esculentus) On Oxidative Stress Induced By Lead Poisoning In Red Sokoto Goat [PDF]

, 2019
M. Adam
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Behavioral shifts mask the success of legislation and outreach for endangered species recovery. [PDF]

Nat Commun
Bakker VJ, Doak DF, Welch A, Burnett LJ, Porras Peña MC, Brandt J, Poessel SA, Kirkland S, Wolstenholme R, Ryan D, Stake M, Punzalan A, Vilchis N, Braham MA, Finkelstein ME.   +14 more
europepmc   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Lead Screening Among Immigrant Children Seeking Humanitarian Protection in New York and Massachusetts, 2022-2024. [PDF]

Public Health Rep
Hunnewell J, Olivo-Freites C, Danaher F, Raju S, Olivo-Freites C, Lim C, Amaya F, LaRocque R, Mohareb AM.   +8 more
europepmc   +1 more source

The Evolution of Lead Extraction [PDF]

, 2009
Melanie Maytin, Laurence M. Epstein
openalex   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source