Results 161 to 170 of about 4,994,390 (315)

Jailed or freed? The lead dilemma in transcatheter tricuspid valve replacement [PDF]

Pascal Defaye, Peggy Jacon, Sandrine Venier   +2 more
openalex   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Aluminum Cobalt, Iron, Lead, Manganese, Mercury, Nickel and Tellurium Detected Among Twenty-Three Metals and Altered Levels of KIM-1 in Urinary Samples of School-Aged Children from Nine Localities in a West-Central State of Mexico: A Cross-Sectional Study

Oliver Mendoza‐Cano, Mónica Ríos‐Silva, Irma González-Curiel, Arlette A. Camacho-delaCruz, Fernanda Romo-García, Herguin Benjamín Cuevas-Arellano, Ana Luz Quintanilla‐Montoya, Miguel A. Martínez-Preciado, Pedro Rincón-Avalos, Ángel Gabriel Hilerio-López, Efrén Murillo‐Zamora   +10 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Evaluating Spanish Translations of Emergency Department Discharge Instructions by a Large Language Model: Tool Validation and Reliability Study. [PDF]

JMIR Form Res
Carreras Tartak JA, Brewster RC, Arango Isaza D, Berumen Martinez A, Grafals A, Adusumilli P, Fitzgerald T, Orcutt R, Nathanson LA, Haimovich AD.   +9 more
europepmc   +1 more source

COMPASS: A multi-physics coupling platform for safety analysis of lead-cooled fast reactors

Zinan Huang, Yuxing Liu, Youpeng Zhang, Yunxiang Li, Wenjun Hu, Yuping Zhou, Hong Jian, Run-Sheng Yang, Xin Su   +8 more
openalex   +1 more source

GA 3 improves flower yield in some cucurbits treated with lead and mercury [PDF]

, 2006
Aisha Saleem Khan, Najma Yaqub Chaudhry
openalex   +1 more source

Ensemble Kalman filter for GAN-ConvLSTM based long lead-time forecasting

, 2023
Meiling Cheng, F. Fang, I. M. Navon, Christopher C. Pain   +3 more
openalex   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source