Results 91 to 100 of about 275,648 (287)
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Editorial: Training and testing in climbing
Frontiers in Sports and Active Living, 2022 Vidar Andersen +3 more
doaj +1 more source
Climbing the ladder: a method for identifying promising copper-lead apatites
8 pages, 9 ...
Sukhenko, Ihor, Karbivskyy, Volodymyr
openaire +2 more sources
The Bolton Dome Fundraiser Film Thesis [PDF]
, 2018 The sport of rock climbing has evolved drastically since its conception, nearly 150 years ago. Recently, climbing has experienced a surge in popularity and has begun to leave noticeable impacts on fragile cliffside ecosystems.
query, fraser
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Analyzing Injury Patterns in Climbing: A Comprehensive Study of Risk Factors
SportsClimbing, a sport with increasing popularity, poses diverse risks and injury patterns across its various disciplines. This study evaluates the incidence and nature of climbing-related injuries, focusing on how different disciplines and climbers’ personal
Markéta Kovářová +2 more
doaj +1 more source
Characteristics of counter-movements in sport climbing: A comparison between experienced climbers and beginners [PDF]
, 2019 学位記番号 ...
Asakawa, Daichi +2 more
core
The GRT Planning System: Backward Heuristic Construction in Forward State-Space Planning
, 2011 This paper presents GRT, a domain-independent heuristic planning system for STRIPS worlds. GRT solves problems in two phases. In the pre-processing phase, it estimates the distance between each fact and the goals of the problem, in a backward direction ...
Refanidis, I., Vlahavas, I.
core +1 more source