Results 91 to 100 of about 6,035,850 (306)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Lead Exposure and Prevention Advisory Committee (LEPAC) meeting : National Center for Environmental Health (NCEH), Centers for Disease Control and Prevention (CDC), December 3, 2021, 9:00 a.m. ET to 4:05 p.m. ET : meeting summary [PDF]

open access: yes
The Lead Exposure and Prevention Advisory Committee (LEPAC) convened on December 3, 2021. Remote participation through a virtual ZOOM meeting was used to hold the meeting.

core  

Systems Biology-Based Analysis Indicates Global Transcriptional Impairment in Lead-Treated Human Neural Progenitor Cells

open access: yesFrontiers in Genetics, 2019
Lead poisoning effects are wide and include nervous system impairment, peculiarly during development, leading to neural damage. Lead interaction with calcium and zinc-containing metalloproteins broadly affects cellular metabolism since these proteins are
Clovis F. Reis   +7 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Lead Poisoning and The Bell Curve [PDF]

open access: yes
A robust environmental health literature demonstrates that preschool lead exposure can cause neurodevelopmental damage and associated adverse impacts on IQ, education, and behavior.
Nevin, Rick
core  

Occupational lead exposure and its dual impact on renal function and reproductive hormones: A case-control study of Nigerian battery chargers

open access: yesJournal of Allied Health Sciences & Medical Research
Occupational lead exposure among battery chargers poses significant risks to renal and reproductive health. This study assessed serum markers of kidney function (urea, creatinine, uric acid) and reproductive hormones (luteinizing hormone [LH ...
Ganiyu O. Adeosun   +5 more
doaj   +1 more source

DNA damage and repair assessed by comet assay in workers exposed to lead in a battery recycling.

open access: yesFrontiers in Genetics, 2015
Occupational exposure to xenobiotic mixtures is an actual concern to public health effects. The automobile battery recycling industry, contribute to lead and cadmium exposure as a mixture for worker in several countries (Palus et al., 2005).
Mahara Valverde   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Monetary benefits of preventing childhood lead poisoning with lead-safe window replacement [PDF]

open access: yes
Previous estimates of childhood lead poisoning prevention benefits have quantified the present value of some health benefits, but not the costs of lead paint hazard control or the benefits associated with housing and energy markets. Because older housing
Berg, Michael   +3 more
core  

Determinants of childhood lead exposure in the postleaded petrol era: The Tooth Fairy cohort from Newcastle upon Tyne [PDF]

open access: yes, 2014
Lead is an environmental contaminant causing irreversible health effects in children. We used dentine lead levels as a measure of early-life lead exposure and explored determinants of lead exposure in children living in Newcastle upon Tyne, a ...
Hodgson, S   +9 more
core   +1 more source

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