Results 251 to 260 of about 14,415,700 (341)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Multiple Interactions in Polar Lead-Free Perovskites toward Highly Stable X-Ray Detection. [PDF]

open access: yesAdv Sci (Weinh)
Qu C   +14 more
europepmc   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

Textured Lead-Free Piezoelectric Ceramics: A Review of Template Effects. [PDF]

open access: yesMaterials (Basel)
Zate TT   +3 more
europepmc   +1 more source

Boosts in Polarization and Piezoelectric Responses of Lead-Free Ferroelectrics through Strain-Enhanced Glassy Coexistent Polars with High Dynamics. [PDF]

open access: yesAdv Sci (Weinh)
He L   +12 more
europepmc   +1 more source

Lead-Free, Sn-Based All-Perovskite Tandem Solar Cells with an Efficiency Over 15. [PDF]

open access: yesSmall
Yoon S   +7 more
europepmc   +1 more source

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