Results 91 to 100 of about 190,957 (265)

Machine Learning-Based Identification of Key Predictors for Lightning Events in the Third Pole Region

ISPRS International Journal of Geo-Information
The Third Pole region, particularly the Hindu–Kush–Himalaya (HKH), is highly prone to lightning, causing thousands of fatalities annually. Skillful prediction and timely communication are essential for mitigating lightning-related losses in such ...
Harshwardhan Jadhav, Prashant Singh, Bodo Ahrens, Juerg Schmidli   +3 more
doaj   +1 more source

Establish a special conservation zone for the captive giant panda

Ecosystem Health and Sustainability, 2018
The giant panda (Ailuropoda melanoleuca) is recognized worldwide as an icon for wildlife conservation. Since the introduction in 1992 of reliable methods for artificial insemination, the population of captive pandas has grown to approximately 350 ...
Yi-ping Chen, Aaron M. Ellison, Yong-long Lu   +2 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Stress and efficiency studies in EFG [PDF]

, 1984
Stress and efficiency studies in EFG were carried out for silicon sheet growth. Methods were developed to quantify influence of dislocation electrical activity on bulk lifetime. A new creep law formulation for silicon stress was developed.
Kalejs, J. P.
core   +1 more source

Viscous regularization and r-adaptive remeshing for finite element analysis of lipid membrane mechanics

, 2007
As two-dimensional fluid shells, lipid bilayer membranes resist bending and stretching but are unable to sustain shear stresses. This property gives membranes the ability to adopt dramatic shape changes. In this paper, a finite element model is developed
Alberts, Ayton, Bacia, Balluffi, Baumgart, Baumgart, Bozic, Božič, Byrd, Canham, Capovilla, Cirak, Cirak, Derényi, Do Carmo, Du, Du, Evans, Evans, Feng, Frey, Fygenson, Gompper, Heinrich, Heinrich, Helfrich, Ho, Hsu, Jaric, Jenkins, Jenkins, Jiang, Jülicher, Jülicher, Kawakatsu, Kraus, Lin Ma, Lipowsky, Nocedal, Noguchi, Noguchi, Powers, Seifert, Seifert, Seifert, Smith, Snapp, Sokolnikoff, Steigmann, Svetina, Svetina, Svetina, Taniguchi, Taniguchi, Toledano, Wang, Wiese, William S. Klug, Wintz, Zhu   +59 more
core   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

JaxoDraw: A graphical user interface for drawing Feynman diagrams

, 2003
JaxoDraw is a Feynman graph plotting tool written in Java. It has a complete graphical user interface that allows all actions to be carried out via mouse click-and-drag operations in a WYSIWYG fashion.
Binosi, D., Theussl, L.
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

The (dis)establishment of gender: Care and gender roles in the family as a constitutional matter [PDF]

, 2015
This article reasons that for women, as constitutional subjects, the emancipatory promise of constitutionalism was—from its inception—fundamentally limited by the entrenchment of the separate spheres tradition.
Rubio-Marín, Ruth
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source