Results 71 to 80 of about 2,872,837 (282)

Diskursus Hermeneutik dalam Paradigma Keislaman dan Kemodernan

open access: yesSubstantia: Jurnal Ilmu-Ilmu Ushuluddin, 2015
Muslim scholars’ interests on hermeneutic have led to the development of the Al-Quran interpretation into various models. Hermeneutic has become the icon in modernization of Al-Quran values in which interpretation revolves around transnational and ...
Nurkhalis Nurkhalis
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Consolidation of Degraded Lime Wooden Support from Heritage Objects Using Two Types of Consolidant

open access: yesBioResources, 2023
The novelty of the research consists in the fact that the decayed wood was taken from an old icon, on which several consolidation treatments were applied, and the improvement indices of the decayed wood (by Anobiidae insects) were also determined.
Anamaria Avram   +2 more
doaj   +2 more sources

Icon of Saint Nicholas

open access: yes, 2020
St. Nicholas was the Defender of Orthodoxy, Wonderworker, Holy Hierarch, Bishop of Myra. The Icon showed him with a halo, dressed in clerical garb, and holding a book of the scriptures in his left hand while making the hand gesture for the sign of the ...
Beards, Daniel E.
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

The Mother of God of the Kanikleion

open access: yesGreek, Roman, and Byzantine Studies, 2001
The lead seal of the 11th/12th century here published offers an image of the Virgin Kiriotissa, but the inscription gives Kanikliotisa; this must invoke an icon of Mary that would have been in the Kanikleion monastery.
George P. Galavaris
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

[sound icon], March 17, 2014 [PDF]

open access: yes, 2014
This is the concert program of the [sound icon] performance on Monday, March 17, 2014 at 8:00 p.m., at the Boston University Concert Hall, 855 Commonwealth Avenue, Boston, Massachusetts.
School of Music, Boston University
core   +1 more source

Machine Learning-Based Identification of Key Predictors for Lightning Events in the Third Pole Region

open access: yesISPRS International Journal of Geo-Information
The Third Pole region, particularly the Hindu–Kush–Himalaya (HKH), is highly prone to lightning, causing thousands of fatalities annually. Skillful prediction and timely communication are essential for mitigating lightning-related losses in such ...
Harshwardhan Jadhav   +3 more
doaj   +1 more source

Gran Torinoís Hmong Lead Bee Vang on Film, Race and Masculinity [PDF]

open access: yesHmong Studies Journal, 2010
Bee Vang, of Minneapolis, played the Hmong lead Thao Vang Lor in Clint Eastwood's 2008 Gran Torino. He was sixteen when he shot the film and had no acting training.
Louisa Schein
doaj  

Home - About - Disclaimer - Privacy