Results 51 to 60 of about 190,957 (265)
Pediatric Blood &Cancer, EarlyView.ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider +4 more
wiley +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
The hardness of the iconic must: Can Peirce’s existential graphs assist modal epistemology? [PDF]
, 2009 The current of development in 20th century logic bypassed Peirce’s existential graphs, but recently much good work has been done by formal logicians excavating the graphs from Peirce’s manuscripts, regularizing them and demonstrating the soundness and ...
Legg, Catherine
core +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Squaring the Circle: In Quest for Sustainability [PDF]
, 2014 Development has been themain strategy in addressing the problemof sustainability since at least the mid-1980s. The results of this strategy have been mixed, if not disappointing.
Shkliarevsky, Gennady
core +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The effectiveness of infiltration in the treatment of enamel hypoplasia
Известия высших учебных заведений. Поволжский регион: Медицинские наукиBackground. The problem of non-carious lesions of the hard tissues of teeth remains relevant in modern dentistry. One of these diseases is enamel hypoplasia, which is a qualitative and quantitative underdevelopment of the enamel caused by a violation of ...
Milyavsha A. Khayrova
doaj +1 more source
Pharmaceutics, 2021 Fluorescently labeled nanoparticles are widely used for evaluating their distribution in the biological environment. However, dye leakage can lead to misinterpretations of the nanoparticles’ biodistribution.
Vasilisa Zhukova +17 more
doaj +1 more source
Ecological IVIS design : using EID to develop a novel in-vehicle information system [PDF]
, 2012 New in-vehicle information systems (IVIS) are emerging which purport to encourage more environment friendly or ‘green’ driving. Meanwhile, wider concerns about road safety and in-car distractions remain.
Brooke J +11 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source