Results 61 to 70 of about 2,872,837 (282)

iCON-MICs at the Masaryk University of Brno (24-24 September, 2023)

open access: yes, 2023
iCOn-MICs, in collaboration with the Masaryk University of Brno, has organized a series of presentations, workshops and a round table focused on climate change, biodiversity and ecology.
alazaro2
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Sensitivity of the tropical Atlantic to vertical mixing in two ocean models (ICON-O v2.6.6 and FESOM v2.5) [PDF]

open access: yesGeoscientific Model Development
Ocean general circulation models still have large upper-ocean biases, including in tropical sea surface temperature, that are possibly connected to the representation of vertical mixing.
S. Bastin   +16 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Moss Icon lyric sheets, 1988

open access: yes, 1988
Lyric sheets distributed by the Annapolis, Maryland punk band Moss Icon at their concert in Washington, D.C. on July 28, 1988 with Fugazi, Ignition and Ulysses.
Moss Icon (Musical group)
core  

Knowledge and Prevalence of common Nutritional Patterns among Non-elite Student Athletes in Lead City University, Ibadan [PDF]

open access: yes, 2023
Nutrition has been seen by many scholars as a branch of science that deals with nutrients particularly in humans. Proper nutrition offers one of the most effective and least costly ways to decrease the burden of many diseases and their ...
OLADAPO, Olawale Oluwaseun   +1 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

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