Results 61 to 70 of about 190,957 (265)

Learning to direct attention: Consequences for procedural task training programs

open access: yesActa Psychologica
Procedural training programs such as augmented and virtual reality programs often present cues that direct trainees' attention to particular locations and/or items to facilitate learning.
Monique D. Crouse
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Embracing Localization Inaccuracy: A Case Study [PDF]

open access: yes, 2012
In recent years, indoor localization has become a hot research topic with some sophisticated solutions reaching accuracy on the order of ten centimeters.
Murphy, Amy L.   +2 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Extrusion-based additive manufacturing of concrete products. Revolutionizing and remodeling the construction industry [PDF]

open access: yes, 2019
Additive manufacturing is one of the main topics of the fourth industrial revolution; defined as Industry 4.0. This technology offers several advantages related to the construction and architectural sectors; such as economic; environmental; social; and ...
Sambucci, Matteo   +2 more
core   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Sensitivity of the tropical Atlantic to vertical mixing in two ocean models (ICON-O v2.6.6 and FESOM v2.5) [PDF]

open access: yesGeoscientific Model Development
Ocean general circulation models still have large upper-ocean biases, including in tropical sea surface temperature, that are possibly connected to the representation of vertical mixing.
S. Bastin   +16 more
doaj   +1 more source

Catching and displaying memory cues for a mobile augmented memory system [PDF]

open access: yes, 2013
This report goes over and details the progress of the 2013 COMP477 project “Augmenting Memory: The Digital Parrot on Mobile Devices” undertaken by Jake Bellamy and supervised by Annika Hinze at the University of Waikato.
Bellamy, Jake, Hinze, Annika
core   +1 more source

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