Results 31 to 40 of about 5,205 (129)
Pre‐Seasonal Treatment With Recombinant Carrier‐Based Birch Vaccine Improves Birch Pollen Allergy
Allergy, EarlyView.We conducted a two stage SCIT trial with GNR‐127 containing a recombinant fusion protein consisting of Bet v 1 and Mal d 1‐derived peptides fused to PreS from HBV. Stage 1 identified two safe maximum tolerated doses (40 μg and 80 μg). In the following Stage 2, five preseasonal injections were well tolerated, induced dose‐dependent allergen‐specific IgG,
Musa R. Khaitov +43 more
wiley +1 more source
American Ethnologist, EarlyView.Abstract An anthropology of horror can serve as a vernacular critique of financial speculation. Drawing on fieldwork in San Pedro, Paraguay, I track horror across three registers: pombero tricksters; plata yvyguy (buried money) as a founding myth of postwar finance; and obligations binding sesame farmers to monsters, patrones, and creditors.
Caroline E. Schuster
wiley +1 more source
Project for Universal Management of Airways: guidelines for tracheal extubation
Anaesthesia, EarlyView.Summary Introduction Risk evaluation, strategy formulation and preparation are important to decreasing the incidence of adverse events associated with tracheal extubation. The focus of this guideline is tracheal extubation, but many of the principles outlined are relevant to all forms of discontinuation of airway management (tracheal extubation ...
Louise Ellard +14 more
wiley +1 more source
Anaesthesia, EarlyView.Summary Introduction Cerebral computed tomography angiography (CTA) is increasingly incorporated into national guidelines to confirm cerebral circulatory arrest during the determination of death using neurological criteria. However, implementation remains limited due to studies showing variable sensitivity.
Romuald Bohatyrewicz +14 more
wiley +1 more source
Acta Obstetricia et Gynecologica Scandinavica, EarlyView.Cesarean section is associated with higher rates of chronic health conditions and pregnancy‐related complications, whereas vaginal delivery is more commonly linked to pelvic floor and perineal complications. These findings emphasize the need for individualized decision‐making and thorough counseling about the risks and benefits of each delivery method.
Katrin Täär +13 more
wiley +1 more source
Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?
British Journal of Pharmacology, EarlyView.Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli +7 more
wiley +1 more source
Child and Adolescent Mental Health, EarlyView.Background Around 20% of 12‐ to 25‐year‐olds experience self‐harm, but interventions deemed both acceptable and effective in reducing self‐harm behaviour are rare. Digital interventions can be effective; however, they often lack sustained engagement and co‐design.
Lindsay H. Dewa +9 more
wiley +1 more source
Clinical Genetics, EarlyView.Beyond diagnosing rare neurodevelopmental disorders like HNRNPU‐RNDD, developing gene‐directed therapies requires overcoming complex hurdles, including spatial, developmental, and cell‐type constraints. Addressing these requires understanding the molecular effects of dosage and chromatin dynamics to deliver precise, effective treatments.
Daniel Aiyedun +3 more
wiley +1 more source
Children &Society, EarlyView.ABSTRACT Research on young people's use of digital devices and platforms demonstrates that their online experiences are deeply situated and contextual, shaped both by individual circumstances and by algorithmically driven systems that personalise content and mediate engagement.
Kaitlyn Regehr +3 more
wiley +1 more source
Journal of Child Psychology and Psychiatry, Volume 66, Issue 4, Page 516-546, April 2025.Proliferation of the term “emotion dysregulation” in child psychopathology parallels the growing interest in processes that influence negative emotional reactivity. While it commonly refers to a clinical phenotype where intense anger leads to behavioral dyscontrol, the term implies etiology because anything that is dysregulated requires an impaired ...
Joseph C. Blader +2 more
wiley +1 more source