Results 31 to 40 of about 3,028,332 (296)

Lead-interacting proteins and their implication in lead poisoning

open access: yes, 2019
Lead is an important heavy metal used worldwide in several applications, especially in industry. People exposed to lead can develop a wide range of symptoms associated with lead poisoning.
Iara Dantas de Souza (8151738)   +2 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

open access: yesFEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa   +4 more
wiley   +1 more source

Functionalizing Micro‐to‐Mesoscopic Electrode Architectures for Regulating Electron Transfer Behaviors in Electrocatalysis

open access: yesAdvanced Functional Materials, EarlyView.
A systematic review is conducted to assess the influence of electrode architecture across micro‐ to mesoscopic length scales on electron‐transfer pathways in electrocatalysis. We discuss the structure‐activity relationships in electrocatalytic applications, including resource recovery and environmental remediation, and provide cost‐effective, efficient
Manshu Zhao   +6 more
wiley   +1 more source

IN VITRO EFFECTS OF LEAD OXIDE ON THE HUMAN ERYTHROCYTE [PDF]

open access: yes, 2012
Lead has no biological function; however, low, and particularly, high levels of exposure have a number of negative consequess for human healt. Despite the number of reports about lead tocicity, very little information has been obtained regarding its ...
Yıldırım, Alperen Kutay
core   +1 more source

Lewis Acid Site Engineering in MOF‐Derived Aluminum Oxide/Carbon Composites for Dechlorination of Waste Plastic Pyrolysis Oil

open access: yesAdvanced Functional Materials, EarlyView.
Controlled carbonization of an Al‐MOF partially decomposes its linkers, exposing coordinatively unsaturated Al centers within an oxide/carbon composite. The resulting Lewis acid sites, rather than surface area, govern organochlorine capture: the composite removes chemically diverse organochlorines from waste plastic pyrolysis oil, outperforms a ...
Seong Cheon Kim   +6 more
wiley   +1 more source

Lead Poisoning: Myoclonus Following Welding Exposure

open access: yesActa Médica Portuguesa, 2017
N/A.
Rubens Gisbert Cury   +2 more
doaj   +1 more source

Spatial Analysis and Lead‐Risk Assessment of Philadelphia, USA

open access: yesGeoHealth, 2022
Childhood lead poisoning is an issue that continues to plague major U.S. cities. Despite efforts by the Philadelphia Department of Public Health to curtail systemic childhood lead poisoning, children continue to be identified with elevated blood lead ...
H. Caballero‐Gómez   +5 more
doaj   +1 more source

Lead pollution: Impact on environment and human health and approach for a sustainable solution

open access: yesEnvironmental Chemistry and Ecotoxicology, 2023
Normally the word pollution states the expulsion of many elements, components, and waste products with a lot of harmful constituents into the natural surroundings in large quantities that interrupts or ruins its aptitude to support the ecosystem ...
Kshyanaprava Raj, Alok Prasad Das
doaj   +1 more source

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