Results 171 to 180 of about 3,177,823 (315)

Lead in archived hair documents a decline in lead exposure to humans since the establishment of the US Environmental Protection Agency. [PDF]

Proc Natl Acad Sci U S A
Cerling TE, Fernandez DP, Smith KR.
europepmc   +1 more source

Underinvestment and Market Structure [PDF]

This paper analyses a dynamic game of investment in R&D or advertising, where current investments change future market conditions. It investigates whether underinvestment can be supported in equilibrium by the threat of escalation in investment outlays ...
Volker Nocke
core  

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Developing monoclonal antibody therapies for measles could lead to adverse pathogen evolution. [PDF]

PLoS Biol
Kennedy DA.
europepmc   +1 more source

Lead equivalent personal protection equipment

, 2017
Henry Knipe, Andrew Murphy, James Hayes
openaire   +1 more source

Amulet™ Shines and Protects; Pacing Battle Intensifies with “More Leads or No Leads”?

Journal of Innovations in Cardiac Rhythm Management, 2022
Ellis, Christopher R., King, Nicholas
openaire   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Respiratory syncytial virus mRNA vaccine-induced immunity and protection against subgroups A and B in mice. [PDF]

Immunohorizons
Lee S, Yoon J, Shooter S, Pak DS, Ha B, Rostad CA, Anderson LJ, Schinazi RF, Kim B.   +8 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

High-capacity nations can unlock momentum for quality marine protection. [PDF]

iScience
Favoretto F, Kumagai JA, López-Sagástegui C, Brannigan D, Driedger A, Sletten J, Colegrove C, Vincent T, Zetterlind V, Guidetti P, Aburto-Oropeza O.   +10 more
europepmc   +1 more source