Results 101 to 110 of about 11,227,924 (260)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The role of LEADER programme in the development of Vámospércs

open access: yes, 2010
A dolgozatban bemutatom az Európai Unió egyik legnépszerűbb vidékfejlesztési programját, a LEADER programot, valamint annak szerepét Vámospércs városának fejlődésében.
Szabó, Gergő
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

The role of LEADER programme in the development of Vásárosnamény

open access: yes, 2014
Dolgozatom célja, hogy bemutassam magát a LEADER programot, annak működését, valamint megvizsgáljam a program hatását Vásárosnamény településen. Munkám során a szekunder adatgyűjtés mellett primer adatokat is gyűjtöttem, aminek forrásául az egyesület ...
Nyirati, Norbert
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

16 CHAPTER 2. LEADER ELECTION Chapter 2 Leader

open access: yes, 2014
Some algorithms (e.g. the slow tree coloring algorithm 4) ask for a special node, a so-called “leader”. Computing a leader is a very simple form of symmetry breaking.
Anonymous Leader Election
core  

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

[Orange Leader Staffers and Printers in 1915]

open access: yes, 1915
Photograph of staffers and printers at the Orange Leader around 1915. Three of them are identified: Matt Larson, far right, Mike Claybar, fourth from right, and Meredith Smith, second from right.

core  

LIDER VERSUS MANAGER, MANAGEMENT VERSUS LEADERSHIP [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2016
There is a very pronounced tendency to confuse leadership with management. Also, the leader-manager issue is intensively discussed and researched.
Angela-Olimpia LOBONEA OLTEAN
doaj  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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