Results 111 to 120 of about 5,437,492 (305)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
The materializing of the LEADER program in the village of Sóshartyán
, 2011 Az általam választott faluban történt LEADER pályázatok jellemzése és elemzése.Gazdasági és Vidékfejlesztési ...
Tóth, Kornél
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Research and extension reduce impact of California energy crunch
California Agriculture, 2001 Michael Reid, James Thompson
doaj +1 more source
Leader Development: Evaluating a Leader Development Program
, 2019 Bárbara Sousa, Catarina Brandão
openaire +3 more sources
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Τοπική ανάπτυξη και πρωτοβουλία Leader: γεωγραφική ανάλυση επενδύσεων στην Ελλάδα
, 2015 Η παρούσα διπλωματική εργασία έχει ως στόχο την ανάλυση των αποτελεσμάτων της εφαρμογής του προγράμματος Leader στον αγροτικό χώρο των διαφόρων περιφερειών της Ελλάδας.
Αλατζάς, Ευάγγελος - Παναγιώτης
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