Results 61 to 70 of about 5,869,436 (291)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

WHF Emerging Leaders Program [PDF]

European Heart Journal, 2017
Huffman, Mark, Perel, Pablo, Eisele, Jean-Luc, Labarthe, Darwin R., Wood, David, Sliwa, Karen, Yusuf, Salim   +6 more
openaire   +4 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Attitudes of Pre-clinical Medical Students towards Psychiatric Patients Before and After an Early Clinical Experience

Canadian Medical Education Journal, 2011
Background:  Stigma or negative discriminatory attitudes towards psychiatric patients are common in the general public. These attitudes are also demonstrated by medical practitioners and by medical students, which can lead to medical harm to psychiatric ...
Abraham Rudnick
doaj  

Perancangan Robot Pengikut berbasis Visual dan Kontrol Logika Samar

Jurnal Elkomika
ABSTRAK Pada penelitian ini dilakukan replikasi teknologi leader-follower (konvoi) pada sebuah purwarupa mobile robot. Purwarupa yang dibuat terdiri dari komponen perangkat keras, program pengolahan citra, dan sistem kontrol logika samar untuk sistem ...
ALI SADIYOKO, AVICENNA FAHRUNASA, TRIANA MUGIA RAHAYU   +2 more
doaj   +1 more source

An Evaluation of Entrepreneurship Orientation within the LEADER+ program in the European Union [PDF]

Investigaciones Regionales - Journal of Regional Research, 2012
This article deals with the currently widely discussed entrepreneurialorientation (EO) and investigates the roles this concept actually plays withinthe LEADER+ development program and its implementation in three Europeanterritories.
Mario Duarte Canever, Alberto Pérez Chueca, Richard Pfeilstetter   +2 more
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Youth inclusion in value chain development: a case of the aquaculture in Nigeria

CABI Agriculture and Bioscience
Many countries in Sub-Saharan Africa (SSA) have made youth inclusion a top priority in their development agendas. This is aimed at overcoming social, technical, and institutional obstacles and providing fair and significant opportunities for the growth ...
Likimyelesh Nigussie, Thai Thi Minh, Sonali Senaratna Sellamuttu   +2 more
doaj   +1 more source

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi, Akito Kawachi, Dan Tomomasa, Eri Watanabe, Yuji Fujita, Yuya Sato, Masahiro Sekiguchi, Kentaro Watanabe, Moe Hidaka, Akihiro Hoshino, Takahiro Kamiya, Masatoshi Takagi, Hirokazu Kanegane, Motohiro Kato   +13 more
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source