Results 61 to 70 of about 91,209 (262)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

WHF Emerging Leaders Program [PDF]

open access: yesEuropean Heart Journal, 2017
Huffman, Mark   +6 more
openaire   +4 more sources

Youth inclusion in value chain development: a case of the aquaculture in Nigeria

open access: yesCABI Agriculture and Bioscience
Many countries in Sub-Saharan Africa (SSA) have made youth inclusion a top priority in their development agendas. This is aimed at overcoming social, technical, and institutional obstacles and providing fair and significant opportunities for the growth ...
Likimyelesh Nigussie   +2 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Programs for the Development of Physician Leaders

open access: yesAcademic Medicine, 2000
Physician leaders are crucial as never before to ensure the proper integration of good care and cost containment; such integration is both a reasonable expectation of patients and essential for the survival of health care delivery systems. In today's health care environment, a critical mass of physician leaders must be developed in a systematic fashion
R W, Schwartz   +3 more
openaire   +3 more sources

LEADER program u Hrvatskoj

open access: yes, 2012
U Republici Hrvatskoj još uvijek nije provedena javna kampanja za implementaciju LEADER programa, vodećeg europskog programa za ruralni razvoj unatoč jasno zacrtanim smjernicama za implemntaciju LEADER-a u IPARD planu za Republiku Hrvatsku. Razlog tome svakako treba potražiti u slaboj kapacitiranosti političkih struktura koje su odgovorne za provedbu ...
Tolić, Snježana   +2 more
openaire   +2 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Do Big 5 Personality Characteristics and Narcissism Predict Engagement in Leader Development?

open access: yesFrontiers in Psychology, 2018
This study examines personality as a predictor of engagement behavior displayed during leader development programs. Leader development engagement behavior (LDEB) is measured by collecting self- and director ratings of behaviors displayed by undergraduate
Carrie A. Blair   +2 more
doaj   +1 more source

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