Results 71 to 80 of about 199,980 (258)

DEVELOPMENT OF INNOVATIVE LEADERSHIP POTENTIAL IN EDUCATION SYSTEM

Образование и наука, 2015
The aim of the research is to reveal the educational formation mechanisms of manager personality, including the ability to operate the intellectual capital at all levels of activities, to disclose innovative competence in dealingwith special problems as ...
A. Y. Ogorodnikov
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Effect of leadership styles on entrepreneurship success: a comparative analysis

Cogent Business & Management
Leadership plays a pivotal role in shaping innovative capacity and entrepreneurial success. While leadership styles have been widely acknowledged as influential in dynamic socio-economic contexts, their transformative potential remains underexplored in ...
Matthew Olusegun Awotunde, Rafiu Adewale Aregbeshola   +1 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

INTELLECTUAL ELITE AS A TECHNOCRATIC CONDITION OF INSTITUTIONAL LEADERSHIP IN PUBLIC ADMINISTRATION

Університети і лідерство, 2015
In this paper carried out theoretical and methodological analysis of the intellectual elite as a technocratic condition of institutional leadership in public administration.
Radmila Wojtowich
doaj  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

A Systematic Literature Review of Female Leadership in Business (2014–2023)

SAGE Open
With the progress of society and the improvement of women’s status, more and more women are beginning to enter leadership positions, showing both their leadership ability and potential.
Chen Chen, Ivan Ka Wai Lai, Tingyue Kuang   +2 more
doaj   +1 more source

Rethinking academic leadership in medical education: From seniority to scholarship and capacity building

Journal of Shalamar Medical & Dental College
Despite the evolving expectations of academic leadership in health professions educaiton, leadership appointments in many low- and middle-income countries, continue to rely predominantly on years of service rather than demonstrated leadership ...
Noori Kiran Naeem, Gohar Wajid
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source