Results 121 to 130 of about 8,922,754 (328)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Employability of women managers in higher education sector: a study on their leadership qualities
The teaching profession both in this country and internationally is, with few exceptions, dominated by women as it has traditionally been seen as a ‘suitable’ job for women.
Amaratunga, Dilanthi +2 more
core
Facilitating the development of leadership qualities in the Foundation Phase [PDF]
Thesis (PhD)--University of Pretoria, 2017.Developing their leadership qualities is one of the best gifts that teachers can give young learners. Childhood is the best time to inculcate leadership qualities; with these qualities, learners can learn to ...
core
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
An Introduction to Leadership - Learning Package
A learning activity about leadership. This is a learning activity to introduce the concept of leadership. It will explore the key principles of leadership itself and examine different leadership styles.
EVOLUTION +4 more
core
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
The research is conducted in the article and theoretical and practical analysis of the characteristics of leadership and the substantiation of the psychological and pedagogical conditions for the formation and development of leadership qualities in ...
Nataliia Machynska +2 more
doaj +1 more source
There has been much research focused on adult conceptions and experiences of leadership and its impact on both individuals and organisations. What has not been investigated as fully, is youth leadership and the contexts within which young people’s ...
Hawthorne, Rachel
core
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source

