Results 81 to 90 of about 8,922,754 (328)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

What is Quality Leadership?

open access: yesAcademic Leadership: The Online Journal, 2010
Leaders can get others on board with decision making through either delegation or empowerment.Through delegation, a leader will, through an expression of authority, determine which tasks will becompleted by which employees (Billikopf, 2003). Followers are delegated tasks and actions.
Misty Lacour   +3 more
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Leadership: Catalyst for Quality and Performance

open access: yesNursing Leadership, 2010
T he Canadian Journal of Nursing Leadership provides a unique opportunity to share ideas and information about innovations in healthcare, seeking new and improved ways of doing things. To stimulate thinking, Lynn Nagel, as editor-in-chief, asked the journal’s editors to discuss their perspectives.
openaire   +3 more sources

Some Ethiopian Women Leaders\u27 Perceptions about Their Leadership

open access: yes, 2017
This research aimed at exploring the perceptions of women leaders on their performance on three key areas of leadership - on ten leadership qualities, type of power they use and their leadership performance - as perceived and assessed by the leaders ...
Tsegay, Tesfay S.
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Leadership: Qualities of the Prophet [PDF]

open access: yes, 2008
In this seven part series, Dr Kasim Randeree addresses leadership qualities of the Prophets in the Qur’ān and extracts lessons for today’s ...
Randeree, Kasim
core   +1 more source

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