Results 141 to 150 of about 863,174 (299)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Analysis of the relationship between leadership style and teacher work motivation in vocational high schools

open access: yesJPPI (Jurnal Penelitian Pendidikan Indonesia)
Leaders who effectively apply a leadership style can realize their goals by providing motivation. The purpose of this research is to find out and obtain information about the leadership style of school principals and teacher work motivation at SMKN 6 ...
Ermita Ermita   +3 more
doaj   +1 more source

Pengaruh Leadership Style terhadap Learning Organization dan Quality Management untuk Meningkatkan Firm Performance (Studi Kasus pada Perusahaan Sektor Non Manufaktur di Surabaya) [PDF]

open access: yes, 2014
Penelitian ini bertujuan untuk mengetahui pengaruh langsung yang signifikan dari leadership style terhadap learning organization, leadership style terhadap quality management , learning organization terhadap firm performance, quality management terhadap
Widjaja, N. (Noviana)
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Do women really make better leaders than men? : an update

open access: yes, 2002
Women are continuing to make a major impact through their participation in organizations and their ownership of businesses and it is reasonable to assume that the number of women taking up significant roles in society will increase in the future.
POUNDER, James S.
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

The association of perceived leadership style and subjective well-being of employees in a tertiary hospital in Germany. [PDF]

open access: yesPLoS One, 2022
Erschens R   +12 more
europepmc   +1 more source

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