Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li +8 more
wiley +1 more source
Growth and senescence of mavuno, marandu, ipyporã and mulato II grasses subjected to stockpiling
The objective of this study was to evaluate, during the stockpiling period, the growth and senescence of marandu, mavuno, ipyporã and mulato II grasses. The experimental design was completely randomized, with four replications.
Bruno Humberto Rezende Carvalho +5 more
doaj
From deficiency to toxicity: Magnesium increases cannabinoid and terpene production in cannabis plants. [PDF]
Morad D, Bernstein N.
europepmc +1 more source
This study successfully engineered vascularized liver organoids (3HLOs) by co‐culturing human reprogrammed hepatocyte‐like cells (hrHLs) with human umbilical vein endothelial cells (HUVECs) and human umbilical mesenchymal stem cells (HUMSCs). Upon implantation, the 3HLOs established functional vascular anastomosis with the host circulation and ...
Kangdi Yang +13 more
wiley +1 more source
Optimizing Planting Density and Nitrogen Application Enhances Root Lodging Resistance and Yield via Improved Post-Anthesis Light Distribution in Sweet Corn. [PDF]
Chang H +7 more
europepmc +1 more source
Novel Antifungal Scaffold Targeting Tubulin Overcomes Sclerotinia Sclerotiorum Resistance
Addressing pesticide resistance, novel chromone‐acylhydrazone hybrids targeting fungal tubulin are synthesized. Compound G24 potently inhibited S. sclerotiorum (EC50 = 0.21µg mL−1) and demonstrated enhanced field performance via microencapsulation, offering a sustainable strategy against resistance and for global food security.
Lihui Shao +5 more
wiley +1 more source
Root system architecture reorganization under decreasing soil phosphorus lowers root system conductance of Zea mays. [PDF]
Bauer FM +6 more
europepmc +1 more source
Effects of temperature and osmotic stress on leaf appearance rate
RP Rawnsley +4 more
openalex
Soybean Auxin Transporter PIN3 Regulates Nitrate Acquisition to Improve Nitrogen Use and Seed Traits
Xu et al. discovers that switching off auxin transporters in soybean, PIN3a and PIN3b, disrupts auxin flow; this triggers ARF‐STF3/4 signal cascade to activate the nitrate importer NPF2.13 and soil nitrogen acquisition. Multi‐year field trials show edited soybeans maintain yield with higher oil content, offering a potential genetic route to improve ...
Huifang Xu +16 more
wiley +1 more source

