Results 281 to 290 of about 338,609 (329)

From Invaginating Site to Deep Lesion: Spatial Transcriptomics Unravels Ectopic Endometrial Penetration Features in Adenomyosis

open access: yesAdvanced Science, EarlyView.
This work utilizes spatial transcriptomics to map the transcriptional landscape of adenomyosis with obvious invagination structure from the invaginating site to deep lesions. By integrating with single‐cell RNA sequencing, this study elucidates the molecular features of invagination, invasion, and fibrosis, and finds the major participants and vital ...
Boyu Li   +19 more
wiley   +1 more source

Epileptiform Activity and Seizure Risk Follow Long‐Term Non‐Linear Attractor Dynamics

open access: yesAdvanced Science, EarlyView.
This study leverages the HAVOK framework to model long‐term, nonlinear attractor dynamics underlying epileptiform activity and seizure risk in epilepsy patients. By identifying key forcing mechanisms driving chaotic transitions, the findings improve seizure risk forecasting over multi‐day cycles and provide a pathway for personalized, data‐driven ...
Richard E Rosch   +4 more
wiley   +1 more source

Macrophage HM13/SPP Enhances Foamy Macrophage Formation and Atherogenesis

open access: yesAdvanced Science, EarlyView.
Previous research suggests that AIP may prevent atherogenic foamy macrophage formation. This study reveals that AIP, via its chaperone interaction with AHR, inhibits p38‐c‐JUN‐mediated transactivation of HM13, which encodes the ERAD protease HM13/SPP. HM13/SPP promotes foamy macrophage formation in addition to atherogenesis and plaque foamy macrophage ...
Yu Cao   +15 more
wiley   +1 more source

Integrating Dense Genotyping with High‐Throughput Phenotyping Empowers the Genetic Dissection of Berry Quality and Resilience Traits in Grapevine

open access: yesAdvanced Science, EarlyView.
Researchers develop advanced tools to study grapevine traits like berry quality and stress resilience. A 200K SNP array and high‐throughput phenotyping enable the identification of loci linked to berry shape, sugar content, acidity, and cold tolerance. Functional validation of genes such as NAC08 reveals roles in cold tolerance.
Yuyu Zhang   +11 more
wiley   +1 more source

Relating Biomass and Leaf Area Index to Non-destructive Measurements in Order to Monitor Changes in Arctic Vegetation

open access: bronze, 2009
Wenjun Chen   +9 more
openalex   +2 more sources

Machine Learning‐Enhanced Optimization for High‐Throughput Precision in Cellular Droplet Bioprinting

open access: yesAdvanced Science, EarlyView.
A high‐throughput droplet‐based cellular bioprinting platform enhanced with machine learning optimizes five key printing parameters—bioink viscosity, nozzle size, printing time, printing pressure, and cell concentration—to enable accurate prediction of droplet size.
Jaemyung Shin   +7 more
wiley   +1 more source

Citrullination of NF‐κB p65 by PAD2 as a Novel Therapeutic Target for Modulating Macrophage Polarization in Acute Lung Injury

open access: yesAdvanced Science, EarlyView.
Peptidyl arginine deiminase 2 (PAD2) plays a key role in regulating macrophage function in Pseudomonas aeruginosa‐induced acute lung injury (ALI). Using single‐cell RNA sequencing and proteomics, a new PAD2‐catalyzed citrullination site on NF‐κB p65 (171 Arginine), modulating macrophage polarization is identified.
Xin Yu   +11 more
wiley   +1 more source

Comparison of Leaf Area Index, Surface Temperature, and Actual Evapotranspiration Estimated Using the METRIC Model and In Situ Measurements. [PDF]

open access: yesSensors (Basel), 2019
Reyes-González A   +6 more
europepmc   +1 more source

Serrated Leaf‐Like N‐Doped Copper Sulfide Enabling Bifunctional Oxygen Reduction/Evolution via Dual‐Mode Cathode Reactions for High Energy Density and Cycle Stability in Zinc–Air Batteries

open access: yesAdvanced Science, EarlyView.
A serrated leaf‐like nitrogen‐doped copper sulfide (N‐CuS) cathode with hybridized N 2p – S 3p orbitals is presented, mesopores for oxygen transport, and a five times larger electrochemical active surface area than Cu. In aerobic conditions, a zinc–air battery with N‐CuS achieves 788 mAh g⁻¹ and 916 Wh kg⁻¹, outperforming Pt/C+RuO₂.
Do Hwan Jung   +8 more
wiley   +1 more source

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