Results 241 to 250 of about 247,178 (286)

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

Advanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang, Wenxuan Zhao, Xiaoming Hu, Yishu Wang, Peidong Yang, Diwei Zheng, Yugang Wang, Guanghui Ma, Min Shi, Wei Wei, Shuang Wang   +10 more
wiley   +1 more source

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

Advanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu, Ting Wang, Jietao Liu, Jiacheng Qin, Bin Yang, Yihang Liu, Pengfei Li, Gaoxue Wang, Fei Ling   +8 more
wiley   +1 more source

A Hydrogen‐Releasing Nanozyme Engineers a Mitochondrial ROS Amplifier for Self‐Sustaining Catalytic Immunotherapy

Advanced Science, EarlyView.
We developed a RhPd‐H nanozyme that integrates enhanced POD‐mimetic catalytic activity with thermally triggered H2 release. H2 shields and reprograms mitochondria to continuously leak endogenous ·O2−. This dual‐path ROS spatially and temporally disrupts redox homeostasis, inducing persistent oxidative stress for tumor suppression and antitumor immunity,
Mingfan Shi, Jingrui Cao, Tong Wu, Guang Yang, YaWen Yang, Shixin Zhang, Wenwen Su, Hongyu Chu, Yangyang Zhao, Shan Jiang, Qiong Wu, Dongxu Jiao, Fangfang Chen   +12 more
wiley   +1 more source

High‐Throughput Screening and Interpretable Machine Learning for Rational Design of Bimetallic Catalysts for Methane Activation

Advanced Science, EarlyView.
ABSTRACT Methane's efficient catalytic removal is vital for sustainable development. Bimetallic catalysts, though promising for methane activation, pose a design challenge due to their complex compositional space. This work introduces an integrated framework that combines high‐throughput density functional theory (DFT) and interpretable machine ...
Mingzhang Pan, Tian Zhang, Jiawei Dong, Yubao Xie, Kaifeng Zhong, Wei Guan, Haiqiao Wei, Changcheng Fu, Yaqiong Su   +8 more
wiley   +1 more source

Advances and Perspectives in Graphene‐Based Quantum Dots Enabled Neuromorphic Devices

Advanced Science, EarlyView.
Graphene‐based QDs are zero‐dimensional carbon nanomaterials with pronounced quantum confinement and tunable electronic structures. Herein, we summarize their synthesis strategies and functionalization methods, and highlight their functional roles and operating mechanisms in devices, as well as recent advances in neuromorphic electronics. We anticipate
Yulin Zhen, Wei Zeng, Zherui Zhao, JiYu Zhao, Ziyan Huang, Zhuo Chen, Kui Zhou, Guanglong Ding, Su‐Ting Han, Ye Zhou   +9 more
wiley   +1 more source

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The effects of group size, leaf size, and density on the performance of a leaf‐mining moth

Journal of Animal Ecology, 2008
1. The effects of two factors, leaf size and group size, on the performance of the Tupelo leafminer, Antispila nysaefoliella (Lepidoptera: Heliozelidae), were examined by fitting growth models to mine expansion data using nonlinear mixed-effects models. 2.
Candace, Low, Simon N, Wood, Roger M, Nisbet   +2 more
openaire   +2 more sources

Pith width, leaf size, and twig thickness

American Journal of Botany, 2021
AbstractPremiseTo support large leaves, many woody plant species evolved a cost‐effective way to thicken twigs. As an extension of E. J. H. Corner's rule that twig diameter increases with leaf size, we hypothesized that pith width also increases with leaf size.
Kalindhi A. Larios Mendieta, J. Gordon Burleigh, Francis E. Putz   +2 more
openaire   +2 more sources

Leaf size and inflorescence size may be allometrically related traits

Oecologia, 1989
"Corner's rules" for plant form relate the degree of branching to branch diameter, and branch diameter to leaf or inflorescence size. We report the first interspecific test of these rules for inflorescence size and branch diameter. We derived a simple corollary of Corner's rules; since leaf size and inflorescence size are both correlated to branch ...
Jeremy, Midgley, William, Bond
openaire   +2 more sources

Leaf longevity in temperate evergreen species is related to phylogeny and leaf size

Oecologia, 2019
Leaf longevity (LL), the amount of time a photosynthetically active leaf remains on a plant, is an important trait of evergreen species, affecting physiological ecology and ecosystem processes. A long LL gives leaves more time to fix carbon but carries higher construction costs, while a short LL allows plants to respond more rapidly to changing ...
Linnea, Smith, Richard B, Primack, Lucy, Zipf, Sarah, Pardo, Amanda S, Gallinat, Zoe A, Panchen   +5 more
openaire   +2 more sources

Is Leaf Size Important for a Leaf-Galling Sawfly (Hymenoptera: Tenthredinidae)?

Environmental Entomology, 1993
We evaluated the importance of leaf size in determining oviposition choice (i.e., gall densities), gall (and larval) size, and larval survivorship for a population of leaf-galling sawflies, Pontania sp. nr. pacifica Marlatt, on arroyo willow, Salix lasiolepis Bentham. Our results did not support the hypothesis that female sawflies prefer to oviposit in
Karen M. Clancy, Peter W. Price, Christopher F. Sacchi   +2 more
openaire   +1 more source