Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Эпилепсия и пароксизмальные состояния, 2020 Decision of the All-Russian Society of Neurologists Presidium 23.12.2019;Russian League Against Epilepsy.
Russian League Against Epilepsy
doaj
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Safety and cosmetic results of trans-submental endoscopic thyroidectomy
Scientific ReportsThe increasing incidence of thyroid tumors, combined with patients’ growing emphasis on cosmetic outcomes, has fueled advancements in endoscopic thyroidectomy techniques.
Guangtai Shen +14 more
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
League Publicity: Cause or Effect of League Failure? [PDF]
Public Opinion Quarterly, 1938 Dr. Potter has been Professor of International Organization at the Graduate Institute of International Studies, Geneva, since I930. Previously he was for twelve years at the University of Wisconsin. He is a' graduate of Harvard, and received the Ph.D. degree from the same institution in I9I8. He has been intimately acquainted with work of the League of
openaire +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Correspondence on “European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) SLE classification criteria item performance” [PDF]
, 2021 Xavier Bossuyt +2 more
openalex +1 more source
Perceptions of the coach-athlete relationship predict the attainment of mastery achievement goals six months later : a two-wave longitudinal study among F.A. Premier League academy soccer players [PDF]
, 2017 All football teams that compete within the F. A. Premier League possess an academy, whose objective is to produce more and better home-grown players that are capable of playing professionally.
Adie +36 more
core +3 more sources