Results 31 to 40 of about 53,482 (256)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Review of Water Leak Detection Methods in Smart Building Applications

Buildings, 2022
In recent years, the identification of water leak detection methods has entered a wide range of fields. Pipeline failures in water distribution networks lead to the loss of a considerable amount of high-quality water.
Nurfarah Anisah Mohd Yussof, Hann Woei Ho   +1 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A Novel Hybrid Internal Pipeline Leak Detection and Location System Based on Modified Real-Time Transient Modelling

Modelling
A This paper proposes a modified real-time transient modelling (MRTTM) framework to address the critical challenge of leak detection and localization in pipeline transmission systems.
Seyed Ali Mohammad Tajalli, Mazda Moattari, Seyed Vahid Naghavi, Mohammad Reza Salehizadeh   +3 more
doaj   +1 more source

An Integrated Approach to Leak Detection in Water Distribution Networks (WDNs) Using GIS and Remote Sensing

Applied Sciences, 2023
Leakages in the water distribution networks (WDNs) are real problems for utilities and other governmental agencies. Timely leak detection and location identification have been challenges.
Rabab Al Hassani, Tarig Ali, Md Maruf Mortula, Rahul Gawai   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Evaluating Acoustic vs. AI-Based Satellite Leak Detection in Aging US Water Infrastructure: A Cost and Energy Savings Analysis

Smart Cities
The aging water distribution system in the United States, constructed mainly during the 1970s with some pipes dating back 125 years, is experiencing significant deterioration leading to substantial water losses.
Prashant Nagapurkar, Naushita Sharma, Susana Garcia, Sachin Nimbalkar   +3 more
doaj   +1 more source

An Effective Method for Gas-Leak Area Detection and Gas Identification with Mid-Infrared Image

Photonics, 2022
Mid-infrared imaging systems are widely applied in gas-leak detection. However, infrared images generally suffer from low contrast and poor quality.
Qi Zhao, Xiaoxi Nie, Dong Luo, Jue Wang, Qiran Li, Wei Chen   +5 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source