Results 51 to 60 of about 193,153 (298)
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Data Leak Detection As a Service: Challenges and Solutions [PDF]
We describe a network-based data-leak detection (DLD) technique, the main feature of which is that the detection does not require the data owner to reveal the content of the sensitive data.
Shu, Xiaokui, Yao, Danfeng (Daphne)
core +1 more source
Pitfall of the Detection Rate Optimized Bit Allocation within template protection and a remedy [PDF]
One of the requirements of a biometric template protection system is that the protected template ideally should not leak any information about the biometric sample or its derivatives. In the literature, several proposed template protection techniques are
Breebaart, J. +4 more
core +2 more sources
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
The aging water distribution system in the United States, constructed mainly during the 1970s with some pipes dating back 125 years, is experiencing significant deterioration leading to substantial water losses.
Prashant Nagapurkar +3 more
doaj +1 more source
Method and apparatus for detecting gross leaks Patent [PDF]
Volume displacement transducer for leak detection in hermetically sealed semiconductor ...
Orner, J. W.
core +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Optical chemical sensor for solving leak detection problems
The main features of the construction of gas analytical leak detection systems are noted, from the point of view of the sensitive element and the test substance (gas) used in the leak tightness control.
Maslennikov Aleksandr +2 more
doaj +1 more source
An Ultrasonic-Based Detection of Air-Leakage for the Unclosed Components of Aircraft
Air-leakage detection is among the most important processes at the assembly stage of unclosed components, especially for large aircraft. A series of air-leakage detecting methods are generally applied during the final assembly, nevertheless, many of them
Yanlin Lyu +6 more
doaj +1 more source

