Results 61 to 70 of about 1,062,639 (299)
Intrinsic leakage of the Josephson flux qubit and breakdown of the two-level approximation for strong driving [PDF]
, 2010 Solid state devices for quantum bit computation (qubits) are not perfect isolated two-level systems, since additional higher energy levels always exist.
Alejandro Ferrón +2 more
core +2 more sources
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
You-qi chuyunObjective Transient processes like leakage and commissioning in CO2 pipeline operation pose simulation challenges due to the unique physical properties and phase behavior of CO2.
Xinyuan MA +6 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Research on leakage hazards of embankments based on 3D electrical resistivity tomography technology
GrađevinarLeakage is a common issue in reservoirs; however, accurately detecting its location and seepage diameter can be challenging owing to complex geological conditions.
Yuehang Zhao +4 more
doaj +1 more source
The Effect of Inlet Swirl on the Rotordynamic Shroud Forces in a Centrifugal Pump [PDF]
, 1992 The role played by fluid forces in determining the rotordynamic stability of a centrifugal pump is gaining increasing attention. The present research investigates the contributions to the rotordynamic forces from the discharge-to-suction leakage flows ...
Acosta, A. J. +3 more
core +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Periodicity-dependence of the ferroelectric properties in BiFeO3/SrTiO3 multiferroic superlattices
, 2007 Artificial superlattices of (BiFeO3)m(SrTiO3)m (m= 1 to 10 unit cells) consisting of multiferroic BiFeO3 and insulating SrTiO3 layers were fabricated on (100)-oriented SrTiO3 substrates by pulsed laser ablation.
B. Kundys +3 more
core +3 more sources