Results 81 to 90 of about 540,883 (315)

The Application of Geosynthetics in Tailings Storage Facilities: A General Review

Mining
This paper is a summary of many of the key findings on the application of geosynthetics in tailings storage facilities. Topics include the compressibility and permeability of tailings, the equations predicting leakage through circular and non-circular ...
Ronald Kerry Rowe, Jiying Fan
doaj   +1 more source

Examination and analysis of the water tightness of watertight doors in nuclear facilities (Water tightness of the watertight doors beyond design conditions)

Nihon Kikai Gakkai ronbunshu, 2020
A test on the water tightness performance of watertight doors was conducted to obtain knowledge on the fragility beyond design conditions. The performance test was conducted on three types of standard single-swinging watertight doors used for nuclear ...
Hideto TAOKA, Nobuo ISHIDA, Takuya TORIYAMA   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Comparison of composite resin and porcelain inlays for restoration of noncarious cervical lesions: An In vitro study

Dental Research Journal, 2018
Background: Composite resin (CR) currently is one of the most commonly used material in restoring noncarious cervical lesions (NCCL) due to its strength and esthetics color but has microleakage problem.
Hui Theng Chee, Wan Zaripah Wan Bakar, Zuryati Ab Ghani, Bennett T Amaechi   +3 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Leakage Power Analysis and Comparison of Deep Submicron Logic Gates

, 2004
Basic combinational gates, including NAND, NOR and XOR, are fundamental building blocks in CMOS digital circuits. This paper analyses and compares the power consumption due to transistor leakage of low-order and high-order basic logic gates. The NAND and
Merrett, Geoff, Geoff Merrett, Bashir M. Al-Hashimi, Al-Hashimi, Bashir M.   +3 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Sub-Clock Power-Gating Technique for Minimising Leakage Power During Active Mode

, 2011
This paper presents a new technique, called sub-clock power gating, for reducing leakage power in digital circuits. The proposed technique works concurrently with voltage and frequency scaling and power reduction is achieved by power gating within the ...
Hill, Stephen, J N Mistry, Mistry, Jatin, D Flynn, S Hill, Flynn, David, Al-Hashimi, Bashir, B M Al-Hashimi   +7 more
core   +1 more source