Results 31 to 40 of about 5,676,493 (290)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Carbon leakage: an overview. CEPS Special Report No. 79, 6 December 2013 [PDF]

, 2013
Carbon leakage is central to the discussion on climate policy, given the confluence of issues that are currently being debated, including the 2030 Energy and Climate Framework and the review of the EU carbon leakage list by 2014.
Roth, Susanna, Marcu, Andrei, Egenhofer, Christian., Stoefs, Wijnand   +3 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Leakage Characteristics and Flow Field Regulation Mechanism of Annular Clearance Sealed Aerostatic Bearings with Conical Straight Teeth on Stator

Machines
To address the issues of sealing leakage and airflow-induced vibration in high-speed turbomachinery, a conical straight-tooth annular clearance sealed hybrid aerostatic/aerodynamic bearing is investigated.
Fusheng Wang, Yongliang Wang
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Research on leakage characteristics of working clearances of hydrogen circulation pump

Frontiers in Energy Research
The volumetric efficiency of the hydrogen circulation pump (HCP) is mainly affected by the amount of leakage in working clearances. Studying the leakage characteristics of working clearances is of great significance for optimizing the performance of the ...
Huanle Zhai, Wei Li, Xiaomeng Chu, Honggang Mu, Chungen Shen   +4 more
doaj   +1 more source

Static Characteristics and Leakage Rates of Smooth Annular Seals Based on a New Solution Method for Gas-Liquid Two-Phase Conditions

Journal of Marine Science and Engineering, 2021
This paper proposes a new solution method for the leakage and static characteristics of smooth annular seal under a homogeneous gas-liquid two-phase flow based on a bulk-flow model.
Chao Zhong, Lulu Zhai, Jia Guo, Baoling Cui, Guoyou Chen   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Study on the Leakage Diagnosis of a Chilled Water Pipeline Network System Based on Pressure Variation Rate Analysis for Climate Change Mitigation

Buildings
In the context of increasing climate variability and extreme weather, chilled water systems face mounting challenges due to amplified heating and cooling demands and prevalent pipe leakages.
Xuan Zhou, Fei Liu, Lisheng Luo, Shiman Peng, Junlong Xie   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source