Results 41 to 50 of about 5,691,566 (247)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Study on the Leakage Diagnosis of a Chilled Water Pipeline Network System Based on Pressure Variation Rate Analysis for Climate Change Mitigation

Buildings
In the context of increasing climate variability and extreme weather, chilled water systems face mounting challenges due to amplified heating and cooling demands and prevalent pipe leakages.
Xuan Zhou, Fei Liu, Lisheng Luo, Shiman Peng, Junlong Xie   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Intentionally Carbon-Doped AlGaN/GaN HEMTs:Necessity for Vertical Leakage Paths [PDF]

, 2014
Dynamic ON-resistance (RON) in heavily carbon doped AlGaN/GaN high electron mobility transistors is shown to be associated with the semi-insulating carbon-doped buffer region.
Šonský, Jan, Caesar, Markus, Croon, Jeroen, Kuball, Martin, Hurkx, Godefridus, Uren, Michael J, Silvestri, Marco   +6 more
core   +1 more source

Brush Seal Performance with Ideal Gas Working Fluid under Static Rotor Condition

Machines
The study investigated how variations in pressure ratio affect the leakage flow of a brush seal for both contact and clearance structures, in which the clearance is measured as the distance between the bristles tip and the rotor surface.
Altyib Abdallah Mahmoud Ahmed, Meihong Liu, Yuchi Kang, Juan Wang, Aboubaker I. B. Idriss, Nguyen Thi Trung Tin   +5 more
doaj   +1 more source

Effect of internal leakage on torque converter characteristics

Advances in Mechanical Engineering, 2020
To understand the effect of internal leakage on the torque field and characteristics of a torque converter (TC), a transient analysis was performed on the internal flow of a TC and the pressure pulsation characteristics of monitoring points in the ...
Xiong Pan, Chen Xinyuan, Sun Hongjun, Zhong Jiping, Zhen Chenping   +4 more
doaj   +1 more source

Evolution law of air leakage and oxidation characteristics of surrounding coal body in bedding gas extraction

Meikuang Anquan, 2023
To explore the development of coal seam fractures around gas extraction borehole and the issue of self-ignition caused by air leakage, a combination of theoretical analysis, field testing, and laboratory experiments was used.
Haihong HE, Hong TANG, Hua LIU, Jun GUO
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Asymptotic information leakage under one-try attacks [PDF]

, 2011
We study the asymptotic behaviour of (a) information leakage and (b) adversary’s error probability in information hiding systems modelled as noisy channels.
Pampaloni, Francesca, Michela Paolini, Michele Boreale, Francesca Pampaloni, Paolini, Michela, Boreale, Michele   +5 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source