Results 61 to 70 of about 9,373,613 (338)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Investigation of Improved Labyrinth Seal Stability Accounting for Radial Deformation
AerospaceThis study examines the labyrinth seal disc of an aero-engine, specifically analysing the radial deformation caused by centrifugal force and heat stress during operation.
Guozhe Ren +4 more
doaj +1 more source
Applied Sciences, 2022 This study introduces a method that can evaluate the efficiency of leakage management practices and devises a formula to set leakage management goals.
Young Hwan Choi +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
Peru’s Experience in Sovereign Debt Management and Litigation: Some Lessons for the Legal Approach to Sovereign Indebtedness [PDF]
, 2010 The paper sheds light upon a specific issue: carbon leakage. Leakage can be understood as an unanticipated net carbon loss or gain, attributable to a climate policy, or reduction activities. Benign leakage effects are harmless.
Monteagudo, Manuel
core +1 more source
Single-Crystal N-polar GaN p-n Diodes by Plasma-Assisted Molecular Beam Epitaxy
, 2017 N-polar GaN p-n diodes are realized on single-crystal N-polar GaN bulk wafers by plasma-assisted molecular beam epitaxy growth. The current-voltage characteristics show high-quality rectification and electroluminescence characteristics with a high on/off
Cho, YongJin +4 more
core +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
A review of mechanical seals tribology and condition monitoring [PDF]
, 2013 Mechanical seals have become one of the most popular sealing systems for rotating machinery because of low leakage and absence of a requirement for routine maintenance.
Ball, Andrew +2 more
core
, 2016 We discuss the effects of built-in fields and contact configuration on the photovoltaic characteristics of ultrathin GaAs solar cells. The investigation is based on advanced quantum-kinetic simulations reaching beyond the standard semi-classical bulk ...
Datta S. +3 more
core +1 more source
, 2020 Impregnation of Phase Change Materials (PCMs) into a porous medium is a promising way to stabilize their shape and improve thermal conductivity which are essential for thermal energy storage and thermal management of small-size applications, such as ...
Dauvergne, Jean-Luc +8 more
core +1 more source