Results 141 to 150 of about 176,939 (311)

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

open access: yesAdvanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins   +9 more
wiley   +1 more source

Janus Photonic Graphics by Stratified Assembly of Two Distinct Colloids

open access: yesAdvanced Functional Materials, EarlyView.
Double‐sided Janus photonic micropatterns with vivid structural colors are fabricated through a single‐step bottom‐up strategy. Density‐driven stratification and depletion‐mediated crystallization of PMMA and PS binary colloids lead to exclusive lattices on opposite surfaces under centrifugal force.
Young Geon Kim   +4 more
wiley   +1 more source

Leakage through defects in geomembrane liners under high hydraulic heads

open access: yes, 2008
textDams are among the most critical of civil engineering structures and are susceptible to damage due to seepage. Geomembranes have been used to minimize seepage problems in dams since 1959. However, geomembranes are vulnerable to damage, in the form of
Weber, Christine Theresa, 1979-
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Advances in Sustainable and Wearable Textile Based Soft Robotics

open access: yesAdvanced Functional Materials, EarlyView.
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas   +6 more
wiley   +1 more source

Optimum time to refurbish a boiler feed pump at Eskom's power stations

open access: yes, 2014
A key focus area in power generation today is to improve equipment and plant efficiency, with this study specifically aimed to determine the optimum time to refurbish a boiler feed pump by analysing the internal wear of the annular seals. The boiler feed
Mortlock, Steven Peter
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Thermally Pre‐Formed Reconfigurable Resistive Random‐Access Memory Crossbar Arrays: A Dual‐Mode Platform for Robust Physically Unclonable Functions and In‐Memory Computing

open access: yesAdvanced Functional Materials, EarlyView.
A reconfigurable RRAM platform utilizing thermally pre‐formed filaments (TPFs) is developed to realize robust hardware security. By exploiting the thermodynamic stochasticity of TPFs, exceptionally reliable physically unclonable functions (PUFs) are achieved.
Seongbin Kwon   +4 more
wiley   +1 more source

Anion‐Exchange‐Enabled Hydrogel Electrolytes With High Zn2+ Transference for Dendrite‐Free Flexible Zinc‐Ion Batteries

open access: yesAdvanced Functional Materials, EarlyView.
A high‐Zn2+‐transference hydrogel electrolyte of ex‐PDADAM is developed via anion exchange at quaternary ammonium sites, achieving high Zn2+ transference number (0.86), ionic conductivity (8.10 mS cm−1), and toughness (51.25 MJ m−3). Symmetric cells are operated stably for over 2000 h, while flexible pouch cells retain 90.9% capacity after 300 cycles ...
Jung Woo Hong   +8 more
wiley   +1 more source

The Interaction of Turbine Inter-Platform Leakage Flow with the Mainstream Flow [PDF]

open access: yes, 2007
Individual nozzle guide vanes (NGVs) in modern aero engines are often cast as a single piece with integral hub and casing endwalls. When in operation there is a leakage flow through the chord-wise inter-platform gaps.
Kevin Reid   +4 more
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Interface Effects in Ultrathin Silicon on Insulator Films

open access: yesAdvanced Functional Materials, EarlyView.
This work establishes a systematic framework to discriminate how bulk and interface phenomena affect charge transport in ultrathin P‐doped silicon‐on‐insulator (SOI) films. For Si films below 15 nm, electrical characterization demonstrates that interface states drive charge transport, shifting the metal‐insulator transition (MIT) critical dopant ...
Andrea Pulici   +8 more
wiley   +1 more source

Experimental measurement of leakage flow in centrifugal blood pump

open access: yes, 2009
In the design of a blood pump, leakage flow study is crucial as high leakage flow is necessary for good washout within the pump, thereby preventing thrombus formation.
Ong, Li Xuan.
core  

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