Results 41 to 50 of about 3,054 (215)

Fluid Flow Equations for Rotordynamic Flows in Seals and Leakage Paths [PDF]

Journal of Fluids Engineering, 2001
Fluid-induced rotordynamic forces produced by the fluid in an annular seal or in the leakage passage surrounding the shroud of a pump or turbine, are known to contribute substantially to the potential excitation forces acting on the rotor. The present research explores some of the important features of the equations governing bulk-flow models of these ...
Hsu, Y., Brennen, C. E.
openaire   +2 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Effect of geometric shape of piston on power loss of sliding part between piston and cylinder in swash plate type piston pump and motor

Nihon Kikai Gakkai ronbunshu, 2018
The power loss due to the friction and the leakage in the sliding part between piston and cylinder of a swash plate type piston pump and motor affects the equipment performance and the efficiency.
Kazuhiko TANAKA, Satoshi MOMOZONO, Keiji KYOGOKU, Yusuke FUJITA   +3 more
doaj   +1 more source

Rancang Bangun Sistem Monitoring dan Pendeteksi Lokasi Kebocoran Pipa Berdasarkan Analisis Debit Air Berbasis IoT

Elektrika, 2020
The purpose of this research is to design and realize a pipe leak detection system that can be monitored with an Android application. Water flow sensor is used to determine the flow of water, with water flow rate analysis it is possible to know the ...
Ardi DwI Prasetya, Haryanto Haryanto, Kunto Aji Wibisono   +2 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Development of a One-Dimensional Model for the Prediction of Leakage Flows in Rotating Cavities Under Non-Uniform Tangential Pressure Distribution

International Journal of Turbomachinery, Propulsion and Power, 2019
Regenerative pumps are characterized by a low specific speed that place them between rotary positive displacement pumps and purely radial centrifugal pumps.
Giulio Cantini, Simone Salvadori, Massimiliano Insinna, Giorgio Peroni, Gilles Simon, Duccio Griffini, Raffaele Squarcini   +6 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Numerical Study on Flow Characteristics in a Francis Turbine during Load Rejection

Energies, 2019
Labyrinth seals are not usually included in the numerical models of hydraulic machinery to simplify the geometric modeling, and thereby reduce the calculation burden.
Daqing Zhou, Huixiang Chen, Jie Zhang, Shengwen Jiang, Jia Gui, Chunxia Yang, An Yu   +6 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source