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Alcoholic liver disease (ALD) is a major liver disease worldwide and can range from simple steatosis or inflammation to fibrosis/cirrhosis, possibly through leaky gut and systemic endotoxemia. Many patients with alcoholic steatohepatitis (ASH) die within
Dong-ha Kim +12 more
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Autoimmune diabetes mellitus and the leaky gut [PDF]
Over the past decade, our understanding of the immune reactivity and, in particular, of autoimmune disorders has witnessed a silent revolution. It has become clear that many, if not all autoimmune diseases entertain an intimate connection to the bacterial gut flora, a cosmos of trillions of different bacteria, forming diverse consortia distributed ...
Peters, A., Wekerle, H.
openaire +3 more sources
Treating Leaky Syndrome in the Over 65s: Progress and Challenges
Shalini Jain,1,2 Francesco Marotta,3 Leila Haghshenas,4 Hariom Yadav1,2,5 1Department of Neurosurgery and Brain Repair, University of South Florida, Tampa, FL, USA; 2USF Center for Microbiome Research, Microbiomes Institute, University of South Florida ...
Jain S, Marotta F, Haghshenas L, Yadav H
doaj
Lubiprostone improves intestinal permeability in humans, a novel therapy for the leaky gut: A prospective randomized pilot study in healthy volunteers. [PDF]
BACKGROUND AND AIMS:The barrier function of the small intestinal mucosa prevents the introduction of undesired pathogens into the body. Breakdown of this barrier function increases intestinal permeability.
Takayuki Kato +13 more
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A Viewpoint on the Leaky Gut Syndrome to Treat Allergic Asthma: A Novel Opinion
Asthma is a common respiratory disease characterized by airway inflammation, airway hyperreactivity, and reversible airflow obstruction. Despite current treatments, the prevalence of asthma has increased markedly over decades.
Masoumeh Kaboli Farshchi PhD +4 more
doaj +1 more source
The impacts of metabolomic changes (reduced short-chain-fatty acids; SCFAs) in uremic condition is not fully understood. Once daily Candida gavage with or without probiotics (different times of administration) for 1 week prior to bilateral nephrectomy ...
Wiwat Chancharoenthana +11 more
doaj +1 more source
Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota [PDF]
Objective The gut microbiota, which is considered a causal factor in metabolic diseases as shown best in animals, is under the dual influence of the host genome and nutritional environment. This study investigated whether the gut microbiota per se, aside
Klopp, Christophe +45 more
core +1 more source
Cruciferous vegetables (Brassica oleracea) confer cytoprotective effects in Drosophila intestines
Varieties and cultivars of the cruciferous vegetable Brassica oleracea are widely presumed to elicit positive influences on mammalian health and disease, particularly related to their indole and sulforaphane content.
James T. Lyles +5 more
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Abnormal Blood Bacteriome, Gut Dysbiosis, and Progression to Severe Dengue Disease
Despite a well-known association between gut barrier defect (leaky gut) and several diseases, data on translocation of pathogen molecules, including bacterial DNA (blood bacteriome), lipopolysaccharide (LPS), and serum (1→3)-β-D-glucan (BG), from the gut
Wiwat Chancharoenthana +10 more
doaj +1 more source
: Heat-stress-induced inflammation may be ameliorated by antioxidant supplementation due to the purported effects of increased production of reactive oxygen species or oxidative stress on the gastrointestinal tract barrier. Thus, study objectives were to
M.A. Abeyta +8 more
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