Results 91 to 100 of about 1,156,542 (355)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Automation, Lean, Six Sigma: Synergies for improving laboratory efficiency [PDF]
Journal of Medical Biochemistry, 2010 The Pathology Services worldwide, surrounded by products are today requesting solutions. The approach aims towards the brain-to-brain cycle between caregivers and laboratory professionals.
Villa Davide
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Journal for the History of KnowledgeRecent developments in the field of global Asia and the global South are paying attention to alternative ways of knowing and historicizing how they circulate.
Eugenia Lean
doaj +1 more source
Estimate solar contribution to the global surface warming using the ACRIM TSI satellite composite
, 2005 We study, by using a wavelet decomposition methodology, the solar signature on global surface temperature data using the ACRIM total solar irradiance satellite composite by Willson and Mordvinov.
B. J. West +11 more
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Flight techniques for the measurement of stability derivatives and aircraft response
, 1965 A method of obtaining aircraft frequency-response from transient response data by Fourier analysis is currently being investigated. This report describes progress that has been made between the commencement of the contract (1st December, 1964) and ...
Laure-Lean, D. W.
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
, 2013 This book gives an account on the progress of C. Rolim Engenharia regarding lean and green targets in recent years. It contains a theoretical introduction, a history of lean and green developments in the company, research papers
Koskela, Lauri
core