Results 91 to 100 of about 1,098,606 (306)
Lean Thinking: Theory, Application and Dissemination [PDF]
, 2014 This book was written and compiled by the University of Huddersfield to share the learnings and experiences of seven years of Knowledge Transfer Partnership (KTP) and Economic and Social Research Council (ESRC) funded projects with the National Health ...
Bamford, David +4 more
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Sugar and Type 2 diabetes [PDF]
, 2016 Background: Consumption of sugar, specifically sugar-sweetened beverages, has been widely held responsible by the media for the global rise in Type 2 diabetes (T2DM).
Lean, Michael E.J., Te Morenga, Lisa
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Construction Innovation: The Implementation of Lean Construction towards Sustainable Innovation [PDF]
, 2011 The prevalent theory of construction has been seen as a hindrance to construction innovation. The concept of lean construction is concerned with the application of lean thinking to the construction industry.
Goulding, Jack Steven +2 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
, 2013 This book gives an account on the progress of C. Rolim Engenharia regarding lean and green targets in recent years. It contains a theoretical introduction, a history of lean and green developments in the company, research papers
Koskela, Lauri
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Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Flight techniques for the measurement of stability derivatives and aircraft response
, 1965 A method of obtaining aircraft frequency-response from transient response data by Fourier analysis is currently being investigated. This report describes progress that has been made between the commencement of the contract (1st December, 1964) and ...
Laure-Lean, D. W.
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