Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Associations of body fat percentage with C-reactive protein levels in Canadian adults with and without osteoarthritis: Findings from the Canadian Longitudinal Study on Aging (CLSA). [PDF]
Marriott KA +7 more
europepmc +1 more source
Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim +3 more
wiley +1 more source
The Impact of the Menopausal Transition on Body Composition and Abdominal Fat Redistribution. [PDF]
Szeliga A, Chedraui P, Meczekalski B.
europepmc +1 more source
Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker +9 more
wiley +1 more source
Accelerated Muscle Strength Decline and Reduced Lean Mass in Adults with Treated Inflammatory Bowel Disease: A NHANES Study. [PDF]
Alzahrani M +5 more
europepmc +1 more source
Obesity and healthy aging: fat, muscle, and bone trade-offs in an era of potent weight-loss pharmacotherapy. [PDF]
Siddiqui S, Tabatabaie V, Aleksic S.
europepmc +1 more source
MASLD versus MAFLD in lean steatotic liver disease: diagnostic overlap, inclusivity, and the metabolically healthy lean phenotype. [PDF]
Elsabaawy M +3 more
europepmc +1 more source
Toward Scientific Rigor: Setting Standards for Indirect Calorimetry Analysis and Reporting. [PDF]
Lieu EL, Herman MA, Hartig SM.
europepmc +1 more source
Global epidemiology of diabetes and prediabetes in lean or non-obese patients with NAFLD: a systematic review and meta-analysis. [PDF]
Li YY +8 more
europepmc +1 more source

