Results 241 to 250 of about 1,156,542 (355)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Cause-specific mortality in lean individuals with metabolic dysfunction-associated steatotic liver disease. [PDF]

Lipids Health Dis
Zhang Z, Lu J, Chen M, Dai L, Xiang Y, Liu Z, Cao Y, Sheng W, Li C, Song D, Zhang L, Ji G.   +11 more
europepmc   +1 more source

Adolescent “Lean PCOS” Is Characterized by Higher Insulin Resistance and Adverse Adipokine Profile

Rachel Whooten, Sheryl L. Rifas‐Shiman, Izzuddin M. Aris, Wei Perng, Jorge E. Chavarro, Emily Oken, Marie‐France Hivert   +6 more
openalex   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

The downregulation of RIZ1 activates the AKT/mTOR in pregnant women with obesity. [PDF]

Sci Rep
Xie X, Yan J, Zhang J, Huang X, Li J.
europepmc   +1 more source

Analysis of Non-Physical Waste Production Variables (Lean Six Sigma) on Project Time Management Through the Mediation of Lean Construction

Rudi Hartono, Slamet Riyadi, Fausta Ari Barata   +2 more
openalex   +2 more sources

A Lean approach to the reengineering of an organization's processes and design

, 2015
Filipa Alves Santos
openalex   +2 more sources

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Systemic MOTS-c levels are increased in adults with obesity in association with metabolic dysregulation and remain unchanged after weight loss. [PDF]

J Clin Transl Endocrinol
Yoon SH, Yuan F, Zhu X, Tang H, Abdurakhimoova D, Krier J, Eirin A, Lerman A, Cohen P, Lerman LO.   +9 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source