Results 31 to 40 of about 15,302 (309)
Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma
Pediatric Blood &Cancer, EarlyView.ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack +12 more
wiley +1 more source
Building & Management, 2018 Editorial : Lean ...
Piña Ramírez, Carolina +2 more
openaire +4 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher +8 more
wiley +1 more source
International Journal for Research in Applied Science and Engineering Technology, 2021 Lean construction is as an effective management tool to enhance the productivity in construction field. Large research is being done in recent past and is an on-going process to adopt lean principles from manufacturing industry to the construction industry.
openaire +1 more source
Lean Construction: Prospects for the German construction industry [PDF]
Lean Construction Journal, 2007 There is little, if any, information available about the range and dissemination of lean concepts among construction companies in Germany. Building on the methodologies and conceptual frameworks used in earlier work in the UK (Common et al., 2000) and the Netherlands (Johansen et al., 2002) this study carried out a similar survey among German ...
Johansen, Eric, Walter, Lorenz
openaire +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
AN INVESTIGATION INTO THE USAGE OF LEAN CONSTRUCTION TECHNIQUES IN NIGERIA
Journal of Construction Project Management and Innovation, 2017 Inadequate implementation of lean construction techniques poses a serious problem to the Nigerian construction process. The usage of lean techniques at the early stage of construction projects results in enhanced environmental performance, waste ...
Olatunji J OLADIRAN
doaj +1 more source
Systems, 2023 Multiple studies are devoted to problems of construction labour productivity and methods of increasing it. These studies contain systematized factors and the main measures that can be applied to influence them.
Kirill Y. Kulakov +2 more
doaj +1 more source