Results 31 to 40 of about 11,060,629 (282)

Lean Design Management in a Major Infrastructure Project in UK

open access: yes, 2019
Lean Design Management (LDM) is a response from the lean construction community to overcome the chaotic design process in the AEC industry. Many tools, processes and methods were adapted to the context of design with limited success.
Simon Abley   +10 more
core   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin   +17 more
wiley   +1 more source

Benefits and Limitations of Lean Tools in the Building Design Process: A Functional and Comparative Analysis

open access: yesApplied Sciences
The design phase is critical in construction projects, as it directly impacts cost, quality, and execution efficiency. However, it suffers from structural deficiencies in communication, coordination, and early problem detection, leading to delays, cost ...
Adriana Luna   +4 more
doaj   +1 more source

Lean Design Management [PDF]

open access: yesArchitectural Engineering and Design Management, 2011
The driver behind this special edition of Architectural Engineering & Design Management is curiosity.
openaire   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad   +9 more
wiley   +1 more source

A Customizable Lean Design Methodology for Maritime [PDF]

open access: yes, 2018
Lean focuses on the reduction of wastes, optimization of processes and consideration of the production of highly customized systems. Over the past decade the maritime industry has been working to apply unique solutions capable of improving their design and development performances by focusing heavily on production time and quality, however work and ...
B. Sullivan, M. Rossi, S. Terzi
openaire   +4 more sources

“We Cannot Talk as a Family”: Complexities of Survivorship Communication Among Hispanic/Latino Young Adult Survivors of Childhood Cancer, Parents, and Clinicians

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Young adult childhood cancer survivors (YA‐CCS) have an increased risk of treatment‐related health complications throughout their lives. Lifelong survivorship care is recommended, yet many YA‐CCS experience disruptions in care during pediatric‐to‐adult transitions and do not receive recommended survivorship care.
Kevin Shanchen Pu   +8 more
wiley   +1 more source

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba   +29 more
wiley   +1 more source

Moving on - beyond lean thinking [PDF]

open access: yes, 2004
Lean Thinking is currently often positioned as the underlying theory of lean production among practitioners and academics, although its originators, Womack and Jones, seem not to have presented it as a theory. This paper endeavors to analyze whether Lean
Koskela, LJ, Koskela, Lauri
core   +2 more sources

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga   +3 more
wiley   +1 more source

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