Results 51 to 60 of about 11,060,629 (282)

Evaluating Lean Facility Layout Designs Using a BWM-Based Fuzzy ELECTRE I Method

open access: yesAxioms, 2022
Selecting a suitable design for a lean facility layout has become a critical issue for a manufacturing company aiming to remove waste or non-value-added activities and implement the optimal facility arrangement. Many quantitative and qualitative criteria
Thi Bich Ha Nghiem, Ta-Chung Chu
doaj   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida   +6 more
wiley   +1 more source

The Impact of Tenapanor on Body Composition and Blood Pressure in Peritoneal Dialysis Patients: A Pilot Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida   +11 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Towards Principles for Designing Lean Intralogistics Systems: Systematic Transfer of Lean Thinking to Reduce Waste in Intralogistics

open access: yesProceedings of the Conference on Production Systems and Logistics
In lean production, the five well-known design principles of value specification, value stream orientation, flow, pull, and pursuit of perfection have proven successful [1].
Langenfeld, Lena   +3 more
doaj   +1 more source

Applying Lean Methods to Healthcare Design [PDF]

open access: yesHERD: Health Environments Research & Design Journal, 2017
There is a natural affinity between evidence-based design (EBD) and the principles of lean design and construction. Events in my life have convinced me that many of the underlying tenets of good design are physiologically based and objective. The same can be said about lean concepts and their ability to make better design possible.There is a natural ...
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Lean Construction – 2007 to 2016 [PDF]

open access: yes, 2016
Aiming at identify main keywords of Recent Works published the annals of the International Group for Lean Construction Conference ( IGLC ) so Get a retrospective of the main ITS applications, actions and tools used lean .It was analyzed all articles ...
Monte, Carlos Eduardo   +2 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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