Results 71 to 80 of about 11,060,629 (282)

Applying lean thinking in construction

open access: yesAlexandria Engineering Journal, 2013
The productivity of the construction industry worldwide has been declining over the past 40 years. One approach for improving the situation is using lean construction.
Remon Fayek Aziz, Sherif Mohamed Hafez
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Technological Trends in Lean Construction for Engineering Design Improvement and Productivity in Civil Engineering Projects: A Systematic Literature Review

open access: yesDesigns
Lean Construction has become a key strategy for improving productivity, reducing waste, and increasing efficiency in civil engineering projects. In parallel, advances in digital technologies have transformed the way engineering design and project ...
Luis Mayo-Alvarez   +3 more
doaj   +1 more source

Lean Communication-Centered Design: A Lightweight Design Process [PDF]

open access: yes, 2016
Lean Communication-Centered Design LeanCCD is a human-computer interaction HCI design process, which consists of conducting a workshop, detailing user goals, combining interaction models with paper sketches, and testing them with users, supported by guides and templates.
Daniel V. C. Ferreira   +1 more
openaire   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Lean construction: Prospects for the German construction industry [PDF]

open access: yes, 2007
There is little, if any, information available about the range and dissemination of lean concepts among construction companies in Germany. Building on the methodologies and conceptual frameworks used in earlier work in the UK (Common et al., 2000) and ...
Walter, Lorenz, Johansen, Eric
core  

Enhancing Pediatric Outpatient Performance through Leadership and Continuous Improvement Culture: The Mediating Role of Lean Healthcare

open access: yesAsia Pacific Journal of Health Management
Objective: This study examines the association of leadership and continuous improvement culture with Lean Healthcare implementation and their subsequent relationship with service performance in a pediatric outpatient clinic.
Astri Anindya Sariza   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Lean, Agile, and BIM relationships in the design of high-rise building projects

open access: yesRevista Ingeniería de Construcción
The design phase of high-rise building projects faces significant challenges, such as frequent changes, low productivity, and poor coordination between teams, which negatively impact project performance. This research analyzes how the integration of Lean,
Javiera Jeréz Lazcano   +2 more
doaj   +1 more source

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