Results 61 to 70 of about 11,060,629 (282)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Integrating lean thinking and spatial design for healthcare operational performance

open access: yesDiscover Health Systems
Hospitals are increasingly adopting lean principles to improve workflow efficiency; however, their integration into spatial design remains limited in operational management research.
Nayma Khan
doaj   +1 more source

Examining the interaction between lean and sustainability principles in the management process of AEC industry

open access: yesAin Shams Engineering Journal, 2018
Architecture, Engineering and Construction (AEC) industry is classified as a huge consumer of natural resources. It consumes 50% of natural material resources, 40% of energy and is responsible for 50% of total waste.
Laila M. Khodeir, Reem Othman
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Review of Lean Design Management: Processes, methods and technologies

open access: yes, 2017
Lean Design Management (LDM) has been used by lean practitioners to manage the design process in construction. Several methods, processes and tools have been successfully implemented, such as the Last Planner System (LPS), Target Value Design (TVD), Set ...
Antti Peltokorpi   +9 more
core   +1 more source

Aplikasi Metode Lean User Experience dan System Usability Scale pada Analisis, Perancangan, dan Evaluasi Antarmuka Aplikasi Mobile

open access: yesJurnal Teknologi Informasi dan Ilmu Komputer
Sistem i-Lab merupakan aplikasi berbasis web untuk mendukung pelaksanaan praktikum di Departement Informatika Universitas Muhammadiyah Malang (UMM).
Gita Indah Marthasari   +2 more
doaj   +3 more sources

Incorporating Lean Construction agent into the Building Standards Act: the Spanish case study

open access: yesOrganization, Technology and Management in Construction: An International Journal, 2017
There is a demand for lean construction in Europe; even though lean construction is still an emerging field and there is growing interest, there are no regulations on this topic.
Brioso Xavier, Humero Antonio
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Three-Dimensional Inverse Design of Low Specific Speed Turbine for Energy Recovery in Cooling Tower System

open access: yesEnergies, 2018
A three-dimensional inverse design of a low specific speed turbine is studied, and a set of design criteria for low specific speed turbine runner is proposed, including blade loading distributions and blade lean angles. The characteristics of the loading
Wei Yang, Xiaoyu Lei, Benqing Liu
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

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