Results 61 to 70 of about 1,404,391 (280)

A literature review on Lean healthcare: implementation strategies, challenges, and future research directions

Cogent Engineering
This study aimed to explore the implementation of Lean strategies in healthcare, evaluate the potential benefits, identify challenges, and highlight future research directions in the field by employing a concept-centric review bolstered by a concept ...
Leonardo H. Talero-Sarmiento, Laura Y. Escobar-Rodríguez, Fabio L. Gomez-Avila, Diana T. Parra-Sanchez   +3 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

A Importância da Metodologia Lean Healthcare para a Qualidade da Assistência nas Emergências

Revista Pró-UniverSUS
A alta demanda por serviços de atendimento de urgência e emergência e as deficiências nos processos de trabalho podem contribuir para a superlotação das emergências. A metodologia Lean Healthcare permite mapear a cadeia de valor, identificar o valor dos
Juliana Nogueira dos Santos, Ranieri Carvalho Camuzi, Benedito Carlos Cordeiro   +2 more
doaj   +1 more source

Construction and validation of an instrument for evaluating Lean Healthcare in healthcare institutions [PDF]

Revista Gaúcha de Enfermagem
Objective: To build and validate an instrument to evaluate Lean Healthcare in healthcare institutions. Method: Methodological study conducted in three stages: 1) Instrument construction; 2) Content validity using the Delphi technique with 14 experts ...
Hellen Maria de Lima Graf Fernandes, Dirceu da Silva, Rosana Ribeiro Tarifa, Edinêis de Brito Guirardello   +3 more
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Improving workflow at the Emergency Department – simple lessons from the lean management concepts [PDF]

European Journal of Translational and Clinical Medicine
Background: Work in the hospital emergency department (ED) is characterized by a significant (and sometimes excessive) number of patients in relation to medical staff and space and high variability of clinical situations, all in conditions of time ...
Ada Lisowska, Ada Lisowska, Jacek Kleszczyński, Jacek Kleszczyński, Arkadiusz Wilczek, Arkadiusz Wilczek, Grzegorz Wolf, Tomasz Holecki   +7 more
doaj   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Application of Lean Healthcare: a case study in a general hospital [PDF]

, 2016
This paper deals with the presence of Lean Production System in hospitals, known as Lean Healthcare. The aim is to identify the applicability of Lean practices in the management of a general hospital. The research method used was a qualitative case study,
Oliveira Rodrigues, Ana Cristina, Affonso Neto, Annibal   +1 more
core   +1 more source